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Clinical trials for Parkinson Disease in United States

252 results

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Vestibular and Cortical Contributions to Transitions in Freezing of Gait in Parkinson's Disease

Study ID: NCT06506058
Start Date: 2025-03-24
End Date: 2029-01-01
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

75

Intervention / Treatment

EVS and EEG

Sponsor

University of Minnesota

Source: clinicaltrials.gov

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A Study of NE3107 in Early Parkinson's

Study ID: NCT06757010
Start Date: 2025-03-26
End Date: 2026-01-02
Study Type

Interventional

Study Phase

Phase2

No. of Participants

60

Intervention / Treatment

Naya 107

Placebo

Sponsor

BioVie Inc.

Source: clinicaltrials.gov

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Sensory Filtering in the Human Basal Ganglia as a Mechanism of Parkinson's Disease

Study ID: NCT05482126
Start Date: 2022-06-08
End Date: 2026-12-31
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

30

Intervention / Treatment

Intraoperative Behavioral Testing

Behavioral Testing

Sponsor

University of Alabama at Birmingham

Source: clinicaltrials.gov

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Natural History Protocol for Movement Disorders

Study ID: NCT05413291
Start Date: 2022-10-17
End Date: 2030-12-31
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

4000

Intervention / Treatment
Sponsor

National Institute of Neurological Disorders and Stroke (NINDS)

Source: clinicaltrials.gov

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Cortical-Basal Ganglia Speech Networks

Study ID: NCT04286308
Start Date: 2020-10-01
End Date: 2027-02
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

80

Intervention / Treatment

electrophysiological data collection

Sponsor

Massachusetts General Hospital

Source: clinicaltrials.gov

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Novel Shoe Device NUSHU to Measure Gait Analysis in Parkinson's Patients

Study ID: NCT06975059
Start Date: 2025-05-30
End Date: 2030-07
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

40

Intervention / Treatment

NUSHU shoe

Sponsor

Weill Medical College of Cornell University

Source: clinicaltrials.gov

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Longitudinal TSPO PET Imaging With [18F]DPA-714 in PPMI (PPMI DPA-714 PET Imaging)

Study ID: NCT06289582
Start Date: 2024-08-14
End Date: 2028-06
Study Type

Interventional

Study Phase

Early_phase1

No. of Participants

60

Intervention / Treatment

[F-18]DPA714 administration IV

Sponsor

University of Alabama at Birmingham

Source: clinicaltrials.gov

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Motor Network Physiology

Study ID: NCT04957095
Start Date: 2022-02-18
End Date: 2028-12-01
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

120

Intervention / Treatment

Apomorphine Injectable Solution

Subcortical Stimulation

Sponsor

University of Texas Southwestern Medical Center

Source: clinicaltrials.gov

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Early Longitudinal Imaging in the Parkinson's Progressive Marker Initiative (PPMI) Using (18F)AV-133 (PPMI AV-133 Prodromal Imaging)

Study ID: NCT07265596
Start Date: 2023-10-30
End Date: 2027-12
Study Type

Interventional

Study Phase

Phase2

No. of Participants

100

Intervention / Treatment

[18F] AV-133 PET Imaging

Sponsor

Michael J. Fox Foundation for Parkinson's Research

Source: clinicaltrials.gov

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Substudy 06C: A Study of Investigational Agents With Pembrolizumab (MK-3475) and Chemotherapy in Participants With First-Line Locally Advanced Unresectable/Metastatic Gastroesophageal Adenocarcinoma (MK-3475-06C/KEYMAKER-U06)

Study ID: NCT06469944
Start Date: 2024-09-20
End Date: 2029-09-12
Study Type

Interventional

Study Phase

Phase2

No. of Participants

160

Intervention / Treatment

Pembrolizumab

Sacituzumab Tirumotecan (sac-TMT)

Capecitabine

Leucovorin

Levoleucovorin

5-Fluorouracil (5-FU)

Oxaliplatin

Patritumab Deruxtecan

Sponsor

Merck Sharp & Dohme LLC

Source: clinicaltrials.gov

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