Thinking of joining a study?

Register your interest

Become a volunteer?

NCT04286308 | RECRUITING | Parkinson Disease

Cortical-Basal Ganglia Speech Networks
Sponsor:

Massachusetts General Hospital

Information provided by (Responsible Party):

Robert Mark Richardson

Brief Summary:

In this research study the researchers want to learn more about brain activity related to speech perception and production.

Condition or disease

Parkinson Disease

Essential Tremor

Dystonia

Intervention/treatment

electrophysiological data collection

Phase

NA

Detailed Description:

Speech production is disrupted in a number of neurological diseases that involve the basal ganglia, including Parkinson's disease (PD) and dystonia. The investigators will use a novel experimental approach and combination of analytic techniques to elucidate the contribution of neural activity in cortical-basal ganglia circuits to the hierarchical control of speech production, in subjects undergoing deep brain stimulation surgery.

Study Type : INTERVENTIONAL
Estimated Enrollment : 80 participants
Masking : NONE
Primary Purpose : BASIC_SCIENCE
Official Title : Cortical-Basal Ganglia Speech Networks
Actual Study Start Date : 2020-10-01
Estimated Primary Completion Date : 2027-02
Estimated Study Completion Date : 2027-02

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years to 85 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • 1. Subjects scheduled for DBS implantation, as determined by the clinical multidisciplinary movement disorders board with definitive diagnosis of Parkinson's disease, essential tremor or dystonia.
  • 2. Subjects able to provide informed consent and comply with task instructions.
  • 3. Subjects 18-85 years old
Exclusion Criteria
  • 1. Subjects with reported hearing loss.
  • 2. Non-English-speaking subjects
Cortical-Basal Ganglia Speech Networks

Location Details

NCT04286308

Please Choose a site

How to Participate

Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.

Locations

RECRUITING

United States, Massachusetts

Massachusetts General Hospital

Boston, Massachusetts, United States, 02114