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Clinical trials

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First-in-Human Study of ATX-295, an Oral Inhibitor of KIF18A, in Patients With Advanced or Metastatic Solid Tumors, Including Ovarian Cancer

Study ID: NCT06799065
Start Date: 2025-04-30
End Date: 2027-08-30
Study Type

Interventional

Study Phase

Phase1

No. of Participants

65

Intervention / Treatment

ATX-295

Sponsor

Accent Therapeutics

Source: clinicaltrials.gov

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Comparison of Maternal Hemodynamics During Spinal Anesthesia with Different Cesarean Delivery Positioning

Study ID: NCT06857162
Start Date: 2025-04-25
End Date: 2025-09-01
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

216

Intervention / Treatment

Positioninng during Cs

Sponsor

Aswan University

Source: clinicaltrials.gov

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PROgram to Enhance Cardiovascular Risk Trough an Intervention of Nutrition in Bipolar Disorder

Study ID: NCT06488573
Start Date: 2026-02
End Date: 2026-12
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

74

Intervention / Treatment

Nutritional intervention

Sponsor

University of Sao Paulo

Source: clinicaltrials.gov

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Safety and Immunogenicity of the Monovalent Influenza Vaccine A (H5N8) (Inactivated, Fragmented and Adjuvanted) in Adults and Older Adults

Study ID: NCT06842173
Start Date: 2025-04-23
End Date: 2026-07
Study Type

Interventional

Study Phase

Phase2

No. of Participants

700

Intervention / Treatment

Monovalent Influenza Vaccine A (H5N8) (Inactivated, Fragmented, and Adjuvanted) 7.5 mcg

Monovalent influenza vaccine type A (H5N8) 15 mcg

Placebo

Sponsor

Butantan Institute

Source: clinicaltrials.gov

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Repeatability of Magnetic Resonance Imaging in Patients With IDH1 Mutant Glioma on Ivosidenib

Study ID: NCT06648473
Start Date: 2025-04-01
End Date: 2025-12-01
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

40

Intervention / Treatment

MRI Scan

Sponsor

Duke University

Source: clinicaltrials.gov

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Youth Mental Health Recovery in the Family After Inpatient Stay

Study ID: NCT06865573
Start Date: 2025-05
End Date: 2026-04
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

70

Intervention / Treatment
Sponsor

University of Vienna

Source: clinicaltrials.gov

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Efficacy and Safety of Intrathecal Morphine for Postoperative Pain Management Following Caesarean Section

Study ID: NCT06797973
Start Date: 2025-06-01
End Date: 2027-06-30
Study Type

Interventional

Study Phase

Phase4

No. of Participants

1312

Intervention / Treatment

Intrathecal Morphine

Placebo (Sodium Chloride Injection, 0.9%)

Sponsor

Zealand University Hospital

Source: clinicaltrials.gov

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Knowledge, Attitudes, and Beliefs About Musculoskeletal Pain Among Primary Care Health Professionals in Spain.

Study ID: NCT06900231
Start Date: 2025-05
End Date: 2025-11
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

300

Intervention / Treatment
Sponsor

University of Lleida

Source: clinicaltrials.gov

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A Phase 3 Single-arm Study of UGN-104 for the Treatment of Low-grade Upper Tract Urothelial Cancer

Study ID: NCT06774131
Start Date: 2025-04-15
End Date: 2027-03-31
Study Type

Interventional

Study Phase

Phase3

No. of Participants

50

Intervention / Treatment

Oven-104

Sponsor

UroGen Pharma Ltd.

Source: clinicaltrials.gov

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Evaluating a Standardized Checklist Bundle for Optimizing Procedural Ergonomics in Endoscopy

Study ID: NCT06195631
Start Date: 2025-04
End Date: 2026-04
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

100

Intervention / Treatment

Standardized Checklist for Optimizing Procedural Ergonomics in Endoscopy (SCOPE- E) Bundle

Sponsor

Wake Forest University Health Sciences

Source: clinicaltrials.gov

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