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Clinical trials for Parkinson Disease in United States

254 results

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Real-World Patient Experiences Using Continuous Subcutaneous Apomorphine Infusion (ONAPGOTM) in the United States:

Study ID: NCT07219927
Start Date: 2025-03-31
End Date: 2027-08-01
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

120

Intervention / Treatment

Observational study

Sponsor

Supernus Pharmaceuticals, Inc.

Source: clinicaltrials.gov

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Effects of Pallidal Deep Brain Stimulation Location on Motor Impairment in Parkinson's Disease

Study ID: NCT05557864
Start Date: 2016-08-25
End Date: 2026-12-31
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

24

Intervention / Treatment

Deep Brain Stimulation

Sponsor

University of Minnesota

Source: clinicaltrials.gov

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The University of Alabama At Birmingham (UAB) Neuroinflammation in Parkinson's Disease-TSPO- Positron Emission Tomography (PET) Substudy

Study ID: NCT03457493
Start Date: 2018-03-22
End Date: 2027-06
Study Type

Interventional

Study Phase

Phase2

No. of Participants

205

Intervention / Treatment

DPA-714-PET/MRI

5-year Follow-up DPA-714-PET/MRI

DPA-714 Metabolite Analysis

Sponsor

University of Alabama at Birmingham

Source: clinicaltrials.gov

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Low Voltage Electrical Stimulation for Depression in Parkinson's Patients

Study ID: NCT06467695
Start Date: 2024-08-01
End Date: 2027-06-30
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

40

Intervention / Treatment

BIOPAC Stimsola

BIOPAC Stimsola Sham (zero amps)

Sponsor

University of South Alabama

Source: clinicaltrials.gov

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Use of CereGate Therapy for Freezing of Gait in PD

Study ID: NCT05292794
Start Date: 2022-04-18
End Date: 2027-07
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

41

Intervention / Treatment

CereGate Software; BSN cDBS Programmer; BSN Burst Programmer

Sponsor

CereGate Inc.

Source: clinicaltrials.gov

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This Clinical Trial is Designed to Evaluate the Safety, Tolerability, Feasibility and Preliminary Efficacy of NouvNeu001 (Human Dopaminergic Progenitor Cells Injection) in Patients With Parkinson's Disease.

Study ID: NCT07102342
Start Date: 2026-01-12
End Date: 2032-09
Study Type

Interventional

Study Phase

Phase1

No. of Participants

5

Intervention / Treatment

Human Dopaminergic Progenitor Cells

Sponsor

iRegene Therapeutics Co., Ltd.

Source: clinicaltrials.gov

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Naturalistic Sleep Assessed by Wearable Devices in Parkinson Disease

Study ID: NCT05348837
Start Date: 2022-05-01
End Date: 2025-12-01
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

15

Intervention / Treatment

Deep brain stimulation

Sponsor

University of Colorado, Denver

Source: clinicaltrials.gov

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A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)

Study ID: NCT06623422
Start Date: 2024-10-21
End Date: 2038-01-26
Study Type

Interventional

Study Phase

Phase3

No. of Participants

680

Intervention / Treatment

Pembrolizumab

Cisplatin

Carboplatin

Pemetrexed

Gemcitabine

Paclitaxel

Intismeran autogene

Placebo

Sponsor

Merck Sharp & Dohme LLC

Source: clinicaltrials.gov

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SAD Study in Patients With Parkinson's Disease and Motor Fluctuations

Study ID: NCT07422675
Start Date: 2026-02-01
End Date: 2027-01-31
Study Type

Interventional

Study Phase

Phase1

No. of Participants

40

Intervention / Treatment

SER-252 (PEOZ-apomorphine)

enFuse

Sponsor

Serina Therapeutics

Source: clinicaltrials.gov

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Stimulating Specific Brain Areas (VOP/VIM) With Electricity to Improve Movement and Muscle Control

Study ID: NCT07056361
Start Date: 2022-12-16
End Date: 2030-12-31
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

60

Intervention / Treatment

Direct cortical stimulation and deep brain stimulation of motor thalamus

Sponsor

Jorge Gonzalez-Martinez

Source: clinicaltrials.gov

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