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Clinical trials for Cancer in United States

7934 results

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Ziftomenib in Combination With Chemotherapy for Children With Relapsed/Refractory Acute Leukemia

Study ID: NCT06376162
Start Date: 2025-03
End Date: 2027-01
Study Type

Interventional

Study Phase

Phase1

No. of Participants

20

Intervention / Treatment

Ziftomen's

Cytarabine

Fludarabine

Sponsor

LLS PedAL Initiative, LLC

Source: clinicaltrials.gov

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A Clinical Trial to Evaluate the Safety, Tolerability and Clinical Efficacy of M3T01 Monotherapy and in Combination With Pembrolizumab and Other Systemic Therapies

Study ID: NCT06719362
Start Date: 2025-10
End Date: 2030-02
Study Type

Interventional

Study Phase

Phase1

No. of Participants

110

Intervention / Treatment

M3T01

Pembrolizumab

Chemoradiation

FOLFOX regimen

Sponsor

Providence Health & Services

Source: clinicaltrials.gov

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Exploration of Personalized Biomarkers During Neoadjuvant Radiation Therapy for Spinal and Sacral Chordoma

Study ID: NCT06463262
Start Date: 2024-06-14
End Date: 2031-07
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

40

Intervention / Treatment

ctDNA

Sponsor

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Source: clinicaltrials.gov

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Abiraterone and Prednisone or Darolutamide for the Treatment of Advanced Prostate Cancer

Study ID: NCT06173362
Start Date: 2023-11-09
End Date: 2027-05
Study Type

Interventional

Study Phase

Phase2

No. of Participants

75

Intervention / Treatment

Abiraterone

Biospecimen Collection

Darolutami

Prednisone

Sponsor

Mamta Parikh

Source: clinicaltrials.gov

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Evaluating Treatment Outcomes Using Darolutamide and Androgen Deprivation Therapy in Patients With Metastatic Hormone-Sensitive Prostate Cancer.

Study ID: NCT06660862
Start Date: 2025-11
End Date: 2029-11
Study Type

Interventional

Study Phase

Phase4

No. of Participants

80

Intervention / Treatment

Darolutami

Physician choice Androgen Deprivation (Hormone) Therapy

Sponsor

University of Chicago

Source: clinicaltrials.gov

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In-home Intravesical Chemotherapy for the Treatment of Bladder Cancer, INVITE Trial

Study ID: NCT06704191
Start Date: 2025-04-21
End Date: 2026-06-06
Study Type

Interventional

Study Phase

Phase2

No. of Participants

40

Intervention / Treatment

BCG Solution

Cystoscopy

Docetaxel

Gemcitabine

Home Health Encounter

Mitomycin

Administration questionnaire

Sponsor

Mayo Clinic

Source: clinicaltrials.gov

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Inherited CAncer REgistry

Study ID: NCT03231891
Start Date: 2017-02-27
End Date: 2035-12
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

10000

Intervention / Treatment
Sponsor

Vanderbilt-Ingram Cancer Center

Source: clinicaltrials.gov

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Pancreatic Cancer Detection Consortium (PCDC) Prospective Cohorts

Study ID: NCT06271291
Start Date: 2024-12-12
End Date: 2029-11-01
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

30000

Intervention / Treatment

Non-Interventional Study

Sponsor

Mayo Clinic

Source: clinicaltrials.gov

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Discontinuation of Maintenance HER-2 Directed Therapy in Long-Term Survivors of Metastatic HER-2 Positive Breast Cancer

Study ID: NCT05959291
Start Date: 2023-07-17
End Date: 2029-07-31
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

20

Intervention / Treatment

Discontinuation of Anti-HER-2 Maintenance Treatment

Sponsor

University of Miami

Source: clinicaltrials.gov

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Orca-T Following Chemotherapy and Total Marrow and Lymphoid Irradiation for the Treatment of Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia or Myelodysplastic Syndrome

Study ID: NCT06195891
Start Date: 2024-05-24
End Date: 2027-06-21
Study Type

Interventional

Study Phase

Phase1

No. of Participants

33

Intervention / Treatment

Biospecimen Collection

Bone Marrow Aspiration

Bone Marrow Biopsy

Dual-Energy Computed Tomography

Echocardiography

Fludarabine

Magnetic Resonance Imaging

Melphalan

Multigated Acquisition Scan

Partially Engineered T-regulatory Cell Donor Graft TRGFT-201

Tacrolimus

Thiotepa

Total Marrow and Lymphoid Irradiation

Sponsor

City of Hope Medical Center

Source: clinicaltrials.gov

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