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NCT05733091 | RECRUITING | Tumors

Assessment of Functional and Symptom Outcomes for Survivors of Paranasal Sinus, Nasopharyngeal and Skull Base Tumors
Sponsor:

M.D. Anderson Cancer Center

Brief Summary:

To learn about the symptoms and changes our patients experience while receiving treatment for sinonasal or nasopharyngeal cancer

Condition or disease

Tumor

Intervention/treatment

Standard of Care

Detailed Description:

Objectives: * To estimate the prevalence and severity of adverse and functional outcomes in survivors of benign and malignant paranasal sinus, nasopharynx and skull base tumors. * To estimate the prevalence of health promotion behaviors during skull base tumor survivorship * To identify possible mediators or predictors of survivorship outcomes and health behaviors in survivors of skull base tumors. * To develop a database of demographic, clinicopathologic, recurrence, survival, functional and patient reported outcomes (PROS) for patients with benign and malignant paranasal sinus, nasopharyngeal and skull base tumors. * To assess the utility and limitations of PROs in evaluating functional impairments and symptom burden in skull base patients.

Study Type : OBSERVATIONAL
Estimated Enrollment : 300 participants
Official Title : Assessment of Functional and Symptom Outcomes for Survivors of Paranasal Sinus, Nasopharyngeal and Skull Base Tumors
Actual Study Start Date : 2018-12-20
Estimated Primary Completion Date : 2029-12-31
Estimated Study Completion Date : 2029-12-31

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion criteria
  • 1. Previously untreated patients with or suspected to have sinonasal malignancy or nasopharyngeal malignancy diagnosis based on either outside pathology report or MD Anderson pathology report.
  • 2. Age ≥ 18 years
  • 3. Plan to obtain the majority of treatment at MDACC including surgery and radiotherapy
  • 4. Ability to understand and willingness to sign written informed consent
  • Exclusion criteria
    • 1. History of the previous solid or liquid malignancies, apart from skin cancers treated with local therapy.
    • 2. Existing neurocognitive impairment that is not the result of sinonasal and nasopharyngeal cancers or is treatment.
    • 3. Previous treatment for sinonasal or nasopharyngeal carcinomas, apart from biopsy.
Assessment of Functional and Symptom Outcomes for Survivors of Paranasal Sinus, Nasopharyngeal and Skull Base Tumors

Location Details

NCT05733091

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Locations

RECRUITING

United States, Texas

M D Anderson Cancer Center

Houston, Texas, United States, 77030