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Clinical trials for Cancer in United States

7934 results

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Testing the Addition of an Anti-cancer Drug, Lenalidomide, to the Usual Combination Chemotherapy Treatment ("EPOCH") for Adult T-Cell Leukemia-Lymphoma (ATLL)

Study ID: NCT04301076
Start Date: 2021-08-31
End Date: 2027-06-30
Study Type

Interventional

Study Phase

Phase1

No. of Participants

30

Intervention / Treatment

Biospecimen Collection

Bone Marrow Biopsy

Computed Tomography

Cyclophosphamide

Doxorubicin Hydrochloride

Etoposide

Lenalidomide

Positron Emission Tomography

Prednisone

Vincristine Sulfate

Sponsor

National Cancer Institute (NCI)

Source: clinicaltrials.gov

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Chlorhexidine Antiseptic Irrigation of the Bowel Segment During Radical Cystectomy and Urinary Diversion

Study ID: NCT06689176
Start Date: 2024-08-01
End Date: 2025-08-01
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

40

Intervention / Treatment

Irrisept® Antimicrobial Wound Lavage

Sponsor

Icahn School of Medicine at Mount Sinai

Source: clinicaltrials.gov

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At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients with Advanced Cancer

Study ID: NCT05969860
Start Date: 2023-08-23
End Date: 2025-06-14
Study Type

Interventional

Study Phase

Phase2

No. of Participants

200

Intervention / Treatment

Clinical Encounter

Home Health Encounter

Quality-of-Life Assessment

Administration questionnaire

Sponsor

Mayo Clinic

Source: clinicaltrials.gov

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A Multilevel Intervention to Improve Adherence to Childhood Cancer Survivorship

Study ID: NCT05448560
Start Date: 2023-01-01
End Date: 2026-08-31
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

240

Intervention / Treatment

Multi-level Intervention of shared model of survivorship care

Comparison Group

Sponsor

Georgetown University

Source: clinicaltrials.gov

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Testing the Addition of the Chemotherapy Drug Lomustine (Gleostine) to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Methylated Glioblastoma

Study ID: NCT05095376
Start Date: 2022-03-28
End Date: 2026-08-08
Study Type

Interventional

Study Phase

Phase3

No. of Participants

306

Intervention / Treatment

Lomustine

Magnetic Resonance Imaging

Photon Beam Radiation Therapy

Administration questionnaire

Temozolomide

Sponsor

NRG Oncology

Source: clinicaltrials.gov

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Pembrolizumab, Lenvatinib and IL-15 Superagonist N-803 in Combination With HER2 Targeting Autologous Dendritic Cell (AdHER2DC) Vaccine in Participants With Advanced or Metastatic Endometrial Cancer

Study ID: NCT06253494
Start Date: 2024-05-14
End Date: 2028-12-31
Study Type

Interventional

Study Phase

Phase2

No. of Participants

60

Intervention / Treatment

AdHER2DC vaccine

Pembrolizumab

N-803

Lenvew

PATHWAY HER2 (4B5) assay

Sponsor

National Cancer Institute (NCI)

Source: clinicaltrials.gov

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Propranolol in Combination With Pembrolizumab and Standard Chemotherapy for the Treatment of Unresectable Locally Advanced or Metastatic Esophageal or Gastroesophageal Junction Adenocarcinoma

Study ID: NCT05651594
Start Date: 2023-03-07
End Date: 2026-03-30
Study Type

Interventional

Study Phase

Phase2

No. of Participants

40

Intervention / Treatment

Biopsy

Biospecimen Collection

Computed Tomography

Fluorouracil

Leucovorin

Oxaliplatin

Pembrolizumab

Propranolol Hydrochloride

Administration questionnaire

Sponsor

Roswell Park Cancer Institute

Source: clinicaltrials.gov

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Communication Strategies to Increase HPV Vaccination Intention

Study ID: NCT06784960
Start Date: 2025-02-06
End Date: 2026-03
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

3689

Intervention / Treatment

Messages

Sponsor

University of Pennsylvania

Source: clinicaltrials.gov

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Comparing Proton Therapy to Photon Radiation Therapy for Esophageal Cancer

Study ID: NCT03801876
Start Date: 2019-03-15
End Date: 2031-12-21
Study Type

Interventional

Study Phase

Phase3

No. of Participants

300

Intervention / Treatment

Carboplatin

Esophandomy

Intensity-Modulated Radiation Therapy

Paclitaxel

Proton Beam Radiation Therapy

Quality-of-Life Assessment

Administration questionnaire

FOLFOX regimen

CAPOX regimen

Docetaxel

5F U

Sponsor

NRG Oncology

Source: clinicaltrials.gov

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A Phase 1/2 Study of Bleximenib in Participants With Acute Leukemia

Study ID: NCT04811560
Start Date: 2021-05-19
End Date: 2027-10-31
Study Type

Interventional

Study Phase

Phase2

No. of Participants

400

Intervention / Treatment

Bleximenib

Sponsor

Janssen Research & Development, LLC

Source: clinicaltrials.gov

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