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Clinical trials for Cancer in United States

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Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

Study ID: NCT04671667
Start Date: 2021-04-27
End Date: 2029-06-30
Study Type

Interventional

Study Phase

Phase2

No. of Participants

188

Intervention / Treatment

Carboplatin

Cisplatin

Computed Tomography

Intensity-Modulated Radiation Therapy

Magnetic Resonance Imaging

Pembrolizumab

Proton Beam Radiation Therapy

Sponsor

National Cancer Institute (NCI)

Source: clinicaltrials.gov

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TUBectomy With Delayed Oophorectomy in High Risk Women to Assess the Safety of Prevention

Study ID: NCT04294927
Start Date: 2020-03-01
End Date: 2040-02-17
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

3000

Intervention / Treatment

Risk-reducing salpingectomy with delayed oophorectomy

Risk-reducing salpingo-oophorectomy

Sponsor

University Medical Center Nijmegen

Source: clinicaltrials.gov

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Zunsemetinib in Combination With Capecitabine in Patients With Hormone Receptor-Positive and HER2-Negative Metastatic Breast Cancer With Bone Metastasis

Study ID: NCT06374459
Start Date: 2025-01-30
End Date: 2032-05-31
Study Type

Interventional

Study Phase

Phase2

No. of Participants

152

Intervention / Treatment

Zumcemetinib

Capecitabine

Zoledronic acid

Denosumab

Sponsor

Washington University School of Medicine

Source: clinicaltrials.gov

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Magnetic Resonance Imaging for Improving Knowledge of Brain Tumor Biology in Patients With Resectable Glioblastoma

Study ID: NCT06090903
Start Date: 2022-04-14
End Date: 2028-04-18
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

50

Intervention / Treatment

Biospecimen Collection

Magnetic Resonance Imaging

Medical Chart Review

Sponsor

Jonsson Comprehensive Cancer Center

Source: clinicaltrials.gov

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A Fluorescent Tumor Marking Agent, Tozuleristide, for Imaging Oral Cavity Squamous Cell Cancer and High-Grade Oral Cavity Dysplasia During Surgery

Study ID: NCT05316688
Start Date: 2024-04-17
End Date: 2027-01-20
Study Type

Interventional

Study Phase

Phase2

No. of Participants

15

Intervention / Treatment

Near Infrared Imaging

Therapeutic Conventional Surgery

Tozulerists

Sponsor

University of Washington

Source: clinicaltrials.gov

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Remote Digital Physiologic Data Collection in Cancer: An MSK Registry Protocol

Study ID: NCT05390827
Start Date: 2022-05-19
End Date: 2026-07
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

3644

Intervention / Treatment
Sponsor

Memorial Sloan Kettering Cancer Center

Source: clinicaltrials.gov

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IGNITE Firefighters' Health

Study ID: NCT06567561
Start Date: 2025-01-09
End Date: 2025-12-30
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

120

Intervention / Treatment

Whole Foods Plant-Based Diet

Usual Firehouse Diet

Sponsor

Stanford University

Source: clinicaltrials.gov

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Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer

Study ID: NCT04221542
Start Date: 2020-03-04
End Date: 2032-03-21
Study Type

Interventional

Study Phase

Phase1

No. of Participants

479

Intervention / Treatment

AMG 509

Abiraterone

Enzalutamide

Sponsor

Amgen

Source: clinicaltrials.gov

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Total Marrow and Lymphoid Irradiation Before Donor Transplant and Cyclophosphamide in Treating Patients With Acute Myeloid Leukemia

Study ID: NCT03467386
Start Date: 2018-03-19
End Date: 2026-04-06
Study Type

Interventional

Study Phase

Phase1

No. of Participants

18

Intervention / Treatment

Allogeneic Hematopoietic Stem Cell Transplantation

Cyclophosphamide

Filgrastim

Laboratory Biomarker Analysis

Quality-of-Life Assessment

Administration Questionnaire

Tacrolimus

Total Marrow Irradiation

Sponsor

City of Hope Medical Center

Source: clinicaltrials.gov

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An Informational and Supportive Care Intervention for Patients With Locally Advanced Rectal Cancer

Study ID: NCT05914766
Start Date: 2023-09-21
End Date: 2028-12
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

80

Intervention / Treatment

PATHWAYS

Enhanced usual care

Sponsor

Massachusetts General Hospital

Source: clinicaltrials.gov

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