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Clinical trials

3307 results

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CongenItal Naevus Cohort for Longitudinal Evaluation

Study ID: NCT06828822
Start Date: 2025-06-01
End Date: 2031-06-01
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

819

Intervention / Treatment

Neurodevelopmental assessment

Meeting with the parents

Patient quality of life assessment

Sponsor

Nantes University Hospital

Source: clinicaltrials.gov

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Post-marketing Surveillance Study for the Safety of Efluelda Tetra Pre-filled Syringe.

Study ID: NCT06694025
Start Date: 2025-10-01
End Date: 2030-12-05
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

670

Intervention / Treatment

Efluelda Tetra Pre-filled syringe

Sponsor

Sanofi

Source: clinicaltrials.gov

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Clinical Trial Assessing the Efficacy and Safety of Dendritic Cell-Based Immunotherapy for Glioblastoma

Study ID: NCT06749925
Start Date: 2026-01
End Date: 2029-01
Study Type

Interventional

Study Phase

Phase3

No. of Participants

186

Intervention / Treatment

Dendritic Cell Vaccine

Pembrolizumab

Placebo

Sponsor

University of Sao Paulo General Hospital

Source: clinicaltrials.gov

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A Phase II Study of Single Tremelimumab With Regular Interval Durvalumab Plus Gemcitabine and Cisplatin in Locally Advanced Unresectable/Metastatic Combined Hepatocellular-cholangiocarcinoma

Study ID: NCT06855225
Start Date: 2025-06
End Date: 2027-04
Study Type

Interventional

Study Phase

Phase2

No. of Participants

29

Intervention / Treatment

Tremelimumab

Durvalumab

Gemcitabine

Cisplatin

Sponsor

Mehmet action

Source: clinicaltrials.gov

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Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies

Study ID: NCT06904066
Start Date: 2025-04-07
End Date: 2029-04-30
Study Type

Interventional

Study Phase

Phase1

No. of Participants

86

Intervention / Treatment

Aldesleukin

cyclophosphamide

fludarabine phosphate

Individual Patient TCR-Transduced PBL

TruSight Oncology (TSO) 500

Sponsor

National Cancer Institute (NCI)

Source: clinicaltrials.gov

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Minocycline in Neurocognitive Outcomes - Sickle Cell Disease

Study ID: NCT05605366
Start Date: 2025-06-01
End Date: 2026-12-15
Study Type

Interventional

Study Phase

Phase1

No. of Participants

30

Intervention / Treatment

Minocycline

Placebo

Sponsor

University of Cincinnati

Source: clinicaltrials.gov

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Parathyroid Allotransplantation in Medically Refractory Hypoparathyroidism

Study ID: NCT05114980
Start Date: 2025-07
End Date: 2028-01
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

5

Intervention / Treatment

Parathyroid Allotransplant

Sponsor

University of Alabama at Birmingham

Source: clinicaltrials.gov

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Restricted or Liberal Fluid for Haemodynamic Resuscitation in Sepsis

Study ID: NCT05453565
Start Date: 2025-11
End Date: 2026-11
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

7838

Intervention / Treatment

Vasopressors

Fluids

Sponsor

Australian and New Zealand Intensive Care Research Centre

Source: clinicaltrials.gov

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Papaverine in Combination With Radiation Therapy for the Treatment of Locally Advanced Rectal Cancer, DINOMITE Trial

Study ID: NCT06834126
Start Date: 2025-06-06
End Date: 2028-01-01
Study Type

Interventional

Study Phase

Phase1

No. of Participants

36

Intervention / Treatment

Biospecimen Collection

Computed Tomography

Consolidation Therapy

Functional Magnetic Resonance Imaging

Gastrointestinal Endoscopy

Magnetic Resonance Imaging

Papaverine

Radiation Therapy

Total Mesorectal Excision

Sponsor

City of Hope Medical Center

Source: clinicaltrials.gov

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Improving Behavioral Health for Caregivers and Children After Pediatric Injury

Study ID: NCT06856057
Start Date: 2025-07-01
End Date: 2028-08-31
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

348

Intervention / Treatment

Caregivers' Aid to Accelerate Recovery after pediatric Emergencies (CAARE)

Sponsor

Medical University of South Carolina

Source: clinicaltrials.gov

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