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Clinical trials

3858 results

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A Study of OTP-01, a Dual Paratopic PD-1/VEGFR2 Antibody, in Patients With Advanced Solid Tumors

Study ID: NCT07266428
Start Date: 2026-01
End Date: 2028-12
Study Type

Interventional

Study Phase

Phase2

No. of Participants

170

Intervention / Treatment

OTP-01

Sponsor

Excellent Pharma Limited

Source: clinicaltrials.gov

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The Impact of Improved Vagal Function on Periaqueductal Gray Connectivity

Study ID: NCT05618067
Start Date: 2026-01
End Date: 2026-12
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

12

Intervention / Treatment

breathing exercise training

Sponsor

Virginia Commonwealth University

Source: clinicaltrials.gov

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This Study Compares Two Different Ways of Cleaning and Shaping Root Canals During Root-canal Treatment: the Step-down Technique and the Step-back Technique. Iu Want to Find Out Which Method Causes Less Pain After the Procedure. Patients Will be Randomly Placed Into One of the Two Groups, Treated Wit

Study ID: NCT07290192
Start Date: 2026-02-01
End Date: 2027-02-01
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

110

Intervention / Treatment

Step down technique

Sponsor

Armed Forces Post Graduate Medical Institute (AFPGMI), Rawalpindi

Source: clinicaltrials.gov

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Optimizing Health Related Quality of Life Measurement in Adolescent and Young Adult Oncology

Study ID: NCT06897137
Start Date: 2026-01
End Date: 2028-01
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

3000

Intervention / Treatment

Surveys/Questionnaires

Sponsor

Wake Forest University Health Sciences

Source: clinicaltrials.gov

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Safety and Immunogenicity of the Live Attenuated Tetravalent Butantan-Dengue Vaccine in Autoimmune Rheumatic Diseases

Study ID: NCT07087912
Start Date: 2026-01-01
End Date: 2028-12-30
Study Type

Interventional

Study Phase

Phase3

No. of Participants

477

Intervention / Treatment

Dengue 1,2,3,4 (attenuated) vaccine

Sponsor

University of Sao Paulo General Hospital

Source: clinicaltrials.gov

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Prediction of Outcome of Interventional Pain Management

Study ID: NCT02774694
Start Date: 2026-01
End Date: 2027-09
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

350

Intervention / Treatment

nociceptive flexion reflex (NFR) threshold ("Paintracker", Dolosys GmbH, Berlin, Germany)

Sponsor

Benno Rehberg-Klug

Source: clinicaltrials.gov

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177Lu-PSMA-617 With Liver Directed Therapy in Metastatic Castration Resistant Prostate Cancer

Study ID: NCT07145177
Start Date: 2026-01-31
End Date: 2030-10-31
Study Type

Interventional

Study Phase

Phase1

No. of Participants

30

Intervention / Treatment

177Lu-PSMA-617

Ablation

Trans-arterial chemoembolization (TACE)

Positron Emission Tomography (PET)/Computerized tomography (CT)

Tumor Biopsy

Questionnaire

Sponsor

University of California, San Francisco

Source: clinicaltrials.gov

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REVEAL Study - Diagnostic Testing for PTSD Using the Senseye Diagnostic Tool

Study ID: NCT07280065
Start Date: 2026-02
End Date: 2026-10
Study Type

Interventional

Study Phase

Phase3

No. of Participants

1900

Intervention / Treatment

Senseye Diagnostic Tool (DT)

Clinician Administered PTSD Scale for DSM-5, Revised Version

Sponsor

Senseye, Inc.

Source: clinicaltrials.gov

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Dermabrasion for Free Flap Aesthetic Enhancement

Study ID: NCT07233200
Start Date: 2026-07-01
End Date: 2028-01
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

40

Intervention / Treatment

Dermabrasion

Sponsor

Milton S. Hershey Medical Center

Source: clinicaltrials.gov

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A Post-marketing Observational Study of Oral Cholera Vaccine

Study ID: NCT07300462
Start Date: 2026-03
End Date: 2027-06
Study Type

Interventional

Study Phase

Phase4

No. of Participants

6000

Intervention / Treatment

Recombinant subunit B/bacterial cholera vaccine (enteric-coated capsules)

Placebo

Sponsor

Shanghai United Cell Biotechnology Co., Ltd

Source: clinicaltrials.gov

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