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Clinical trials

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A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (mCRC)

Study ID: NCT07011576
Start Date: 2025-07
End Date: 2027-06
Study Type

Interventional

Study Phase

Phase2

No. of Participants

60

Intervention / Treatment

fruquintinib

FOLFIRI (Irinotecan, 5-Fluorouracil, and Leucovorin)

Sponsor

SCRI Development Innovations, LLC

Source: clinicaltrials.gov

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Milk Free From A1-Type β-Casein on Inflammation, Gastrointestinal Tolerance, and Pregnancy Outcomes

Study ID: NCT06980376
Start Date: 2025-07
End Date: 2026-09
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

100

Intervention / Treatment

a2 UHT milk

Conventional UHT Milk

Sponsor

a2 Milk Company Ltd.

Source: clinicaltrials.gov

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Human Umbilical Cord Blood Infusion in Patients with Acute Ischemic Stroke (AIS)

Study ID: NCT06040476
Start Date: 2025-09
End Date: 2028-08
Study Type

Interventional

Study Phase

Phase2

No. of Participants

39

Intervention / Treatment

hUCB

Sponsor

StemCyte, Inc.

Source: clinicaltrials.gov

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MMulti-Immune HR; Multi-Target Immunotherapy for High-Risk Multiple Myeloma

Study ID: NCT07029776
Start Date: 2025-07-01
End Date: 2032-04-01
Study Type

Interventional

Study Phase

Phase2

No. of Participants

50

Intervention / Treatment

teclistamab+daratumumab followed by talquetamab+daratumumab followed by duration treatment with daratumumab and lenalidomide extended/maintenance

melphalan (MEL)-based hematopietic stem cell transplantation (HSCT) followed by drug therapy

Sponsor

University of Arkansas

Source: clinicaltrials.gov

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Feasibility, Acceptability and Preliminary Efficacy of the New Iteration of the Innovative Smartphone-based Care Solution for Women With Breast Cancer Undergoing Chemotherapy (iCareBreast+): A Pilot Study Research Proposal

Study ID: NCT06977360
Start Date: 2025-07
End Date: 2025-12
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

40

Intervention / Treatment

Routine care

Routine care + iCareBreast+ mobile app

Sponsor

National Cancer Centre, Singapore

Source: clinicaltrials.gov

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A Study of the Safety and Exploratory Efficacy of Oral AFA-281 in Patients with Alcohol Use Disorder

Study ID: NCT06710431
Start Date: 2025-10-01
End Date: 2027-12-01
Study Type

Interventional

Study Phase

Phase2

No. of Participants

36

Intervention / Treatment

AFA-281

Sponsor

Afasci Inc

Source: clinicaltrials.gov

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ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas

Study ID: NCT06838676
Start Date: 2025-07
End Date: 2035-07
Study Type

Interventional

Study Phase

Phase2

No. of Participants

60

Intervention / Treatment

ACT001

Sponsor

Nationwide Children's Hospital

Source: clinicaltrials.gov

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Effectiveness of a Guided Mental Health Chatbot STARS for Youth Living in Lithuania

Study ID: NCT07012876
Start Date: 2025-09
End Date: 2028-06-30
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

262

Intervention / Treatment

STARS (Scalable Technology for Adolescents and youth to Reduce Stress)

Basic psychoeducation

Sponsor

Vilnius University

Source: clinicaltrials.gov

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New Care Pathway Using Automated Dynamic Laximetry

Study ID: NCT07028476
Start Date: 2025-09-01
End Date: 2027-09-01
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

80

Intervention / Treatment

Automated Dynamic Laximetry

MRI

Sponsor

University Hospital, Angers

Source: clinicaltrials.gov

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A Phase III Trial of HRS-1893 in Patients With Obstructive Hypertrophic Cardiomyopathy

Study ID: NCT07021976
Start Date: 2025-08
End Date: 2026-11
Study Type

Interventional

Study Phase

Phase3

No. of Participants

216

Intervention / Treatment

HRS-1893 Tablets

HRS-1893 Placebo Tablets

Sponsor

Shandong Suncadia Medicine Co., Ltd.

Source: clinicaltrials.gov

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