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Clinical trials

2728 results

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A Study to Compare the Effectiveness and Safety of T1695 Versus Ciclosporin in Participants With Moderate to Severe Vernal Keratoconjunctivitis

Study ID: NCT07169695
Start Date: 2026-03-02
End Date: 2027-01-21
Study Type

Interventional

Study Phase

Phase2

No. of Participants

120

Intervention / Treatment

Slit Lamp Examination

Far Best Corrected Visual Acuity (BCVA)

T. 1695

Cyclosporine

Corneal fluorescein staining score on modified Oxford scale

Sponsor

Thea Laboratories

Source: clinicaltrials.gov

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A Study Comparing the Clinical Benefit of Finerenone Versus a Fixed Dose Combination (FDC) of Extended-Release Torsemide and Spironolactone in Patients With Hypertension and Chronic Kidney Disease

Study ID: NCT07223502
Start Date: 2025-12-01
End Date: 2026-10
Study Type

Interventional

Study Phase

Phase3

No. of Participants

30

Intervention / Treatment

Combination Product: FDC of spironolactone and ER torsemide

Combination Product: Stabilized doses of loop diuretic and finerenone

Sponsor

Sarfez Pharmaceuticals, Inc.

Source: clinicaltrials.gov

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SERS-Based Serum Molecular Spectral Screening for Lung Cancer Type

Study ID: NCT06775002
Start Date: 2026-04-05
End Date: 2026-11-20
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

223

Intervention / Treatment

Serum Raman spectroscopy intelligent diagnostic system

Sponsor

Fuzhou General Hospital

Source: clinicaltrials.gov

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A Single-centre Study Comparing a Non-invasive Lactate Sensor to Standard Invasive Measurements in Patients Undergoing Coronary Artery Bypass Surgery.

Study ID: NCT06597253
Start Date: 2025-12-02
End Date: 2026-07-31
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

20

Intervention / Treatment

Lactate sensor

Sponsor

Queen Mary University of London

Source: clinicaltrials.gov

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Testing the Safety of the Anti-cancer Drug, Sn-117m-DTPA, for Advanced Cancers That Have Spread to Bones

Study ID: NCT06982222
Start Date: 2025-12-31
End Date: 2027-02-12
Study Type

Interventional

Study Phase

Phase1

No. of Participants

24

Intervention / Treatment

Biospecimen Collection

Bone Scan

Computed Tomography

Positron Emission Tomography

PSMA PET Scan

Single Photon Emission Computed Tomography

Technetium TC-99m

Tin Sn 117m Pentetate

Sponsor

National Cancer Institute (NCI)

Source: clinicaltrials.gov

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Combining Immunotherapy and Radiation Therapy to Help Patients Avoid Bladder Removal After Treatment Shrinks Muscle Invasive Bladder Cancer, BRIGHT Trial

Study ID: NCT07061964
Start Date: 2026-06-01
End Date: 2027-07-31
Study Type

Interventional

Study Phase

Phase2

No. of Participants

111

Intervention / Treatment

Biospecimen Collection

Computed Tomography

Cystoscopy

Magnetic Resonance Imaging

Pembrolizumab

Photon Beam Radiation Therapy

Positron Emission Tomography

Administration Questionnaire

Transurethral Resection of Bladder Tumor

Sponsor

National Cancer Institute (NCI)

Source: clinicaltrials.gov

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Evaluating a Decreased Dose of Radiation Therapy to the Elective Neck for the Treatment of HPV-Related Oropharyngeal Cancer, ENLIGHT Trial

Study ID: NCT07178301
Start Date: 2026-03-20
End Date: 2031-03-20
Study Type

Interventional

Study Phase

Phase2

No. of Participants

100

Intervention / Treatment

Computed Tomography

Nasopharyngeal Laryngoscopy

Positron Emission Tomography

Administration Questionnaire

Radiation Therapy

Sponsor

Northwestern University

Source: clinicaltrials.gov

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Safety and Tolerability of Difelikefalin in Adolescents on Haemodialysis With Moderate-to-Severe Pruritus

Study ID: NCT06593392
Start Date: 2025-12-29
End Date: 2029-08-30
Study Type

Interventional

Study Phase

Phase2

No. of Participants

18

Intervention / Treatment

Diphelikephalin

Sponsor

Vifor Fresenius Medical Care Renal Pharma

Source: clinicaltrials.gov

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Clinical Trial Evaluating Safety and Efficacy of Resomelagon on Dengue Infection (RESOVIR-2)

Study ID: NCT06917001
Start Date: 2026-02
End Date: 2027-12
Study Type

Interventional

Study Phase

Phase2

No. of Participants

120

Intervention / Treatment

Resomelagon

Placebo

Standard Treatment

Sponsor

Federal University of Minas Gerais

Source: clinicaltrials.gov

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The Effect of a Stepped-care Metacognition-based Intervention on Managing Fear of Cancer Recurrence

Study ID: NCT06181331
Start Date: 2026-01-01
End Date: 2027-12-31
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

300

Intervention / Treatment

eConquerFear

eHealthMaintenance

ConquerFear

eConquerFear+eHealthMaintenance

Sponsor

The University of Hong Kong

Source: clinicaltrials.gov

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