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Clinical trials

4405 results

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Personalizing the Use of Pembrolizumab for Patients Who Have a Strong Response in Early Triple Negative Breast Cancer

Study ID: NCT06606730
Start Date: 2025-01-01
End Date: 2039-06-01
Study Type

Interventional

Study Phase

Phase3

No. of Participants

2454

Intervention / Treatment

Pembrolizumab

Deescalation

Sponsor

UNICANCER

Source: clinicaltrials.gov

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A Study to Evaluate the Safety, Tolerability and Efficacy of RZ-001 in Combination with Valganciclovir (VGCV) and Atezolizumab/Bevacizumab in Subjects with Hepatocellular Carcinoma

Study ID: NCT06695026
Start Date: 2024-12
End Date: 2027-10
Study Type

Interventional

Study Phase

Phase2

No. of Participants

45

Intervention / Treatment

RZ-001 Dose 1

RZ-001 Dose 2

RZ-001 Dose 3

Sponsor

Rznomics, Inc.

Source: clinicaltrials.gov

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The Effect of a Methylprednisolone Taper on Outcomes Following Total Knee Arthroplasty

Study ID: NCT06489626
Start Date: 2025-01-01
End Date: 2025-12-01
Study Type

Interventional

Study Phase

Phase4

No. of Participants

100

Intervention / Treatment

Methylprednisolone 4 milligram Tab

Dexamethasone injection

Sponsor

F. Johannes Plate

Source: clinicaltrials.gov

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YN001-004 in Patients With Coronary Atherosclerosis in Australia

Study ID: NCT06700720
Start Date: 2024-12-16
End Date: 2025-09-11
Study Type

Interventional

Study Phase

Phase2

No. of Participants

12

Intervention / Treatment

Dose 1 YN001

Dose 2 YN001

Evolocumab

Sponsor

Beijing Inno Medicine Co., Ltd.

Source: clinicaltrials.gov

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Interstitial Lung Disease Exacerbations Study

Study ID: NCT06685874
Start Date: 2025-01
End Date: 2026-01
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

1500

Intervention / Treatment
Sponsor

Royal Devon and Exeter NHS Foundation Trust

Source: clinicaltrials.gov

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Pre-hospital Administration of Fibrinogen in Trauma-Induced Coagulopathy

Study ID: NCT06582420
Start Date: 2025-01-01
End Date: 2025-12-31
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

52

Intervention / Treatment

Fibrinogen concentrate

Standard trauma care

Sponsor

Arco Ribeirinho Local Health Unit

Source: clinicaltrials.gov

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A Swedish Internet CBT for Prolonged Grief Disorder: a Three-armed RCT

Study ID: NCT06667674
Start Date: 2024-12
End Date: 2027-07
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

270

Intervention / Treatment

iCBT for prolonged grief

Active control

Sponsor

Uppsala University

Source: clinicaltrials.gov

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Stemchymal® for Polyglutamine Spinocerebellar Ataxia

Study ID: NCT06397274
Start Date: 2025-06-01
End Date: 2028-06-01
Study Type

Interventional

Study Phase

Phase2

No. of Participants

20

Intervention / Treatment

Stemchymal

Placebo

Sponsor

Steminent US, Inc.

Source: clinicaltrials.gov

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Effect of Intranasal Oxytocin on Emotion Recognition and Acute Psycho-Social Stress-induced Cortisol Increase in Patients With Central Diabetes Insipidus and Healthy Controls

Study ID: NCT06676774
Start Date: 2025-01-10
End Date: 2027-01-31
Study Type

Interventional

Study Phase

Phase2

No. of Participants

42

Intervention / Treatment

Oxytocin nasal spray

Placebo

Sponsor

University Hospital, Basel, Switzerland

Source: clinicaltrials.gov

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Pulse Radiotherapy to Overcome Metastatic Immune System Evasion in Lung Cancer

Study ID: NCT06622174
Start Date: 2025-04
End Date: 2027-08
Study Type

Interventional

Study Phase

Phase1

No. of Participants

32

Intervention / Treatment

Pulse radiotherapy

Sponsor

Huda Bahig

Source: clinicaltrials.gov

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