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Clinical trials

2753 results

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TCRαβ-depleted Progenitor Cell Graft With Early Memory T-cell DLI, Plus Selected Use of Blinatumomab, in naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies

Study ID: NCT07052370
Start Date: 2025-12
End Date: 2030-12
Study Type

Interventional

Study Phase

Phase1

No. of Participants

30

Intervention / Treatment

Thymoglobulin

Cyclophosphamide

Fludarabine

Thiotepa

Melphalan

Meaty

Filgrastim

Blinatumomab

CliniMACS

Sponsor

St. Jude Children's Research Hospital

Source: clinicaltrials.gov

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Characterization of Primary Central Nervous System Diffuse Large B Cell Lymphoma (PCNS-DLBCL) by Multiomic Approach

Study ID: NCT07147751
Start Date: 2026-04
End Date: 2029-12
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

100

Intervention / Treatment
Sponsor

International Extranodal Lymphoma Study Group (IELSG)

Source: clinicaltrials.gov

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A Study of Mitapivat in Participants With Sickle Cell Disease and Nephropathy

Study ID: NCT06286046
Start Date: 2026-03
End Date: 2028-12
Study Type

Interventional

Study Phase

Phase2

No. of Participants

40

Intervention / Treatment

meetpiwat

Sponsor

Agios Pharmaceuticals, Inc.

Source: clinicaltrials.gov

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Pediatric Acute Respiratory Distress Syndrome (ARDS) Management Trial

Study ID: NCT07123961
Start Date: 2026-01-01
End Date: 2030-06-30
Study Type

Interventional

Study Phase

Phase2

No. of Participants

160

Intervention / Treatment

High Driving Pressure Mechanical Ventilation

Low Driving Pressure Mechanical Ventilation

Sponsor

Children's Hospital of Philadelphia

Source: clinicaltrials.gov

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Prognostic Power of the VEXUS Score in Septic Shock: Effectiveness in Mortality Prediction

Study ID: NCT07124741
Start Date: 2026-03-30
End Date: 2026-08
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

100

Intervention / Treatment

Serial VEXUS Ultrasound Evaluation

Sponsor

Antalya Training and Research Hospital

Source: clinicaltrials.gov

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Phase 2 Study to Assess the Safety and Efficacy of Subcutaneous Blinatumomab in Patients With Measurable Residual Disease Positive B-cell Acute Lymphoblastic Leukemia

Study ID: NCT07192237
Start Date: 2026-02-27
End Date: 2032-10-12
Study Type

Interventional

Study Phase

Phase2

No. of Participants

40

Intervention / Treatment

Blinatumomab

Sponsor

M.D. Anderson Cancer Center

Source: clinicaltrials.gov

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A Study of GM-XANTHO in Pressure Ulcer Patients

Study ID: NCT05199077
Start Date: 2026-09-01
End Date: 2029-04-30
Study Type

Interventional

Study Phase

Phase2

No. of Participants

58

Intervention / Treatment

GM-Blonde

Sponsor

Xantho Biotechnology Co., LTD

Source: clinicaltrials.gov

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Photobiomodulation for Cancer-Related Cognitive Impairment

Study ID: NCT05855694
Start Date: 2025-12
End Date: 2028-12
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

30

Intervention / Treatment

THOR LED Photobiomodulation Helmet - Therapeutic

THOR LED Photobiomodulation Helmet - Control

Sponsor

Arash Asher, MD

Source: clinicaltrials.gov

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Knee Arthroscopy for Pain Control

Study ID: NCT06701175
Start Date: 2025-12
End Date: 2026-10
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

72

Intervention / Treatment

Nerve Block

Portal Anesthesia

Sponsor

University of Alabama at Birmingham

Source: clinicaltrials.gov

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Effect of Iodine-containing Multiple Micronutrient During Lactation on Infant Neurodevelopment

Study ID: NCT05901766
Start Date: 2026-01-01
End Date: 2027-04-01
Study Type

Interventional

Study Phase

Phase4

No. of Participants

600

Intervention / Treatment

UNIMAP Multiple Micronutrient Supplement

Sponsor

Brown University

Source: clinicaltrials.gov

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