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Clinical trials

2753 results

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Trial of Zanzalintinib (XL092) in Combination With Immunotherapy in Patients Who Progress on Adjuvant Therapy in Clear Cell RCC

Study ID: NCT06863311
Start Date: 2025-12
End Date: 2028-12
Study Type

Interventional

Study Phase

Phase2

No. of Participants

70

Intervention / Treatment

XL092

Nivolumab

Sponsor

Than Runcie

Source: clinicaltrials.gov

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Comparison of HYBRID Versus Two-Stent Strategies in Unprotected True Left MAIN Bifurcation

Study ID: NCT07159737
Start Date: 2026-01-01
End Date: 2030-01-01
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

1708

Intervention / Treatment

Two-stent strategy

Hybrid Strategy

Sponsor

Sultanah Bahiyah Hospital

Source: clinicaltrials.gov

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A Patient Navigation Intervention for the Improvement of Risk Management Among Women at High Risk of Breast Cancer

Study ID: NCT06950008
Start Date: 2026-01-10
End Date: 2026-12-31
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

75

Intervention / Treatment

Educational Intervention

Patient Navigation

Survey Administration

Telephone-Based Intervention

Sponsor

Ohio State University Comprehensive Cancer Center

Source: clinicaltrials.gov

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Efficacy of Propofol Combination With Either Ketamine, Dexmedetomidine or Midazolam for Sedation During Upper Gastrointestinal Endoscopic Procedures

Study ID: NCT07190612
Start Date: 2025-12
End Date: 2026-03
Study Type

Interventional

Study Phase

Phase4

No. of Participants

75

Intervention / Treatment

Dexmedetomidine and propofol

Midazolam and propofol

ketamine and propofol

Sponsor

Ain Shams University

Source: clinicaltrials.gov

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Efficacy and Safety of 3D185 Monotherapy in Subjects With Previously Treated Locally Advanced or Metastatic Cholangiocarcinoma

Study ID: NCT05039892
Start Date: 2026-12
End Date: 2028-06
Study Type

Interventional

Study Phase

Phase2

No. of Participants

50

Intervention / Treatment

3D 185

Sponsor

3D Medicines (Beijing) Co., Ltd.

Source: clinicaltrials.gov

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Testing the Addition of an Anti-Cancer Drug, Camonsertib, to Radiation Therapy for Recurrent Head and Neck Squamous Cell Carcinoma

Study ID: NCT07156227
Start Date: 2025-12-26
End Date: 2029-05-31
Study Type

Interventional

Study Phase

Phase1

No. of Participants

39

Intervention / Treatment

Biospecimen Collection

Camonsertib

Computed Tomography

Positron Emission Tomography

Stereotactic Body Radiation Therapy

Sponsor

National Cancer Institute (NCI)

Source: clinicaltrials.gov

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A Study to Learn About Salanersen's (BIIB115) Effects on Movement and Its Safety When Given Before Symptoms Appear in Babies With Genetically Diagnosed Spinal Muscular Atrophy (SMA)

Study ID: NCT07221669
Start Date: 2026-01-30
End Date: 2032-05-29
Study Type

Interventional

Study Phase

Phase3

No. of Participants

30

Intervention / Treatment

Salanersen

Sponsor

Biogen

Source: clinicaltrials.gov

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A Study Comparing the Clinical Benefit of Finerenone Versus a Fixed Dose Combination (FDC) of Extended-Release Torsemide and Spironolactone in Patients With Hypertension and Chronic Kidney Disease

Study ID: NCT07223502
Start Date: 2025-12-01
End Date: 2026-10
Study Type

Interventional

Study Phase

Phase3

No. of Participants

30

Intervention / Treatment

Combination Product: FDC of spironolactone and ER torsemide

Combination Product: Stabilized doses of loop diuretic and finerenone

Sponsor

Sarfez Pharmaceuticals, Inc.

Source: clinicaltrials.gov

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A Clinical Trial of Iron Supplementation for Youth With ADHD and Restless Sleep

Study ID: NCT07061470
Start Date: 2026-03-01
End Date: 2027-07-31
Study Type

Interventional

Study Phase

Phase2

No. of Participants

70

Intervention / Treatment

Ferrous Sulfate

Placebo

Sponsor

Hugo W. Moser Research Institute at Kennedy Krieger, Inc.

Source: clinicaltrials.gov

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Longitudinal Deep Phenotyping of Central Mechanisms in Dysosmia: A Pilot Study Using Electrobulbogram (EBG), Functional MRI (fMRI), and Diffusion-Weighted Imaging (DWI)

Study ID: NCT07149428
Start Date: 2025-11-10
End Date: 2029-10-14
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

80

Intervention / Treatment
Sponsor

National Institute on Deafness and Other Communication Disorders (NIDCD)

Source: clinicaltrials.gov

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