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Clinical trials for Parkinson Disease in United States

252 results

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Longitudinal TSPO PET Imaging With [18F]DPA-714 in PPMI (PPMI DPA-714 PET Imaging)

Study ID: NCT06289582
Start Date: 2024-08-14
End Date: 2028-06
Study Type

Interventional

Study Phase

Early_phase1

No. of Participants

60

Intervention / Treatment

[F-18]DPA714 administration IV

Sponsor

University of Alabama at Birmingham

Source: clinicaltrials.gov

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Studies of Brain and Body Interaction

Study ID: NCT03672266
Start Date: 2018-08-01
End Date: 2026-07-01
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

100

Intervention / Treatment
Sponsor

Rutgers University

Source: clinicaltrials.gov

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[18F]F-DOPA Imaging in Patients With Autonomic Failure

Study ID: NCT04246437
Start Date: 2020-02-04
End Date: 2027-02-01
Study Type

Interventional

Study Phase

Phase1

No. of Participants

40

Intervention / Treatment

[18F]FDOPA

Carbidopa 200mg oral dose

Entacapone 400mg oral dose

Sponsor

Daniel Claassen

Source: clinicaltrials.gov

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A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)

Study ID: NCT06623422
Start Date: 2024-10-21
End Date: 2038-01-26
Study Type

Interventional

Study Phase

Phase3

No. of Participants

680

Intervention / Treatment

Pembrolizumab

Cisplatin

Carboplatin

Pemetrexed

Gemcitabine

Paclitaxel

Intismeran autogene

Placebo

Sponsor

Merck Sharp & Dohme LLC

Source: clinicaltrials.gov

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Cognitive Decline Following Deep Brain Stimulation

Study ID: NCT05822388
Start Date: 2023-04-01
End Date: 2026-03-31
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

80

Intervention / Treatment

Deep Brain Stimulation Surgical Procedures as Part of Routine Clinical Care

Sponsor

Medical University of South Carolina

Source: clinicaltrials.gov

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Pathways Mediating Impaired Postural Control in Parkinson's Disease

Study ID: NCT06464029
Start Date: 2024-06-01
End Date: 2027-06-10
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

120

Intervention / Treatment
Sponsor

University of Minnesota

Source: clinicaltrials.gov

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A Multicenter Study to Evaluate Safety, Tolerability, and Clinical Responses of DSP-1083 Into Subjects With Parkinson's Disease

Study ID: NCT06753331
Start Date: 2024-12-18
End Date: 2030-12-15
Study Type

Interventional

Study Phase

Phase2

No. of Participants

25

Intervention / Treatment

DSP-1083 implantation

Sham surgery treatment

Sponsor

Sumitomo Pharma America, Inc.

Source: clinicaltrials.gov

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A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Thalamotomy for the Treatment of Medication-Refractory Tremor Dominant Idiopathic Parkinson's Disease

Study ID: NCT04991831
Start Date: 2022-04-28
End Date: 2027-12
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

50

Intervention / Treatment

Unilateral thalamotomy

Sponsor

InSightec

Source: clinicaltrials.gov

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Electrophysiology-based DBS Programming for PD

Study ID: NCT07348705
Start Date: 2026-01-15
End Date: 2031-01-15
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

30

Intervention / Treatment

Clinician-based DBS programming

Maximum Beta power-based DBS programming

Broad-band electrophysiology-based DBS programming

Sponsor

University of Florida

Source: clinicaltrials.gov

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Novel DBS Stimulation Patterns for Treatment of Parkinson's Disease

Study ID: NCT04799470
Start Date: 2021-05-10
End Date: 2026-04
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

10

Intervention / Treatment

Novel DBS stimulation patterns

Sponsor

University of Nebraska

Source: clinicaltrials.gov

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