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Clinical trials for Parkinson Disease in United States

252 results

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Colonoscopic Detection of Phosphorylated Alpha-synuclein for Parkinson's Diagnosis

Study ID: NCT07204652
Start Date: 2025-09-03
End Date: 2029-09
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

20

Intervention / Treatment

No Intervention: Observational Cohort

Sponsor

CND Life Sciences

Source: clinicaltrials.gov

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Virtual tES Device Treatment for Parkinson's Disease Motor Symptoms

Study ID: NCT07182058
Start Date: 2026-01-01
End Date: 2026-04-01
Study Type

Interventional

Study Phase

Phase2

No. of Participants

30

Intervention / Treatment

Transcranial Electrical Stimulation Device

Sponsor

U: The Mind Company

Source: clinicaltrials.gov

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Treating Parkinson's Disease Through Transplantation of Autologous Stem Cell-Derived Dopaminergic Neurons

Study ID: NCT06687837
Start Date: 2025-04-29
End Date: 2028-12
Study Type

Interventional

Study Phase

Phase1

No. of Participants

8

Intervention / Treatment

autologous dopaminergic cell implantation

Sponsor

Jeffrey S. Schweitzer, MD, PhD

Source: clinicaltrials.gov

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Rock Steady Boxing: A Community Based In Person Class

Study ID: NCT05773612
Start Date: 2023-03-07
End Date: 2026-04-30
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

150

Intervention / Treatment

Rock Steady Boxing Class

Sponsor

University of St. Augustine for Health Sciences

Source: clinicaltrials.gov

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Elucidating the Role of Cholinergic Degeneration in Cognitive Fluctuations in Lewy Body Dementia

Study ID: NCT07284290
Start Date: 2025-12-08
End Date: 2029-11
Study Type

Interventional

Study Phase

Phase4

No. of Participants

120

Intervention / Treatment

Syn-One skin biopsy

Multi modal MRI

Assessment of dynamic EEG features over 48-hour periods across all study aims

Plasma biomarkers

Galantamine HBr extended-release 8mg capsules (8mg ER).

Sponsor

Virginia Commonwealth University

Source: clinicaltrials.gov

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Imaging Depression in Parkinson's Disease

Study ID: NCT06402955
Start Date: 2024-09-01
End Date: 2029-12-01
Study Type

Interventional

Study Phase

Phase2

No. of Participants

120

Intervention / Treatment

11C-UCB-J

ketamine hydrochloride

Sponsor

Yale University

Source: clinicaltrials.gov

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Study of Biodistribution, Metabolism, Excretion and Brain Uptake 18F-JSS20-183A

Study ID: NCT06932809
Start Date: 2025-05-09
End Date: 2030-04
Study Type

Interventional

Study Phase

Early_phase1

No. of Participants

90

Intervention / Treatment

18F-JSS20-183A PET

Brain MRI

Amyloid PET

Neurological Assessments

Sponsor

University of Pennsylvania

Source: clinicaltrials.gov

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Light Therapy Intervention in Individuals With Parkinson's Disease

Study ID: NCT06916260
Start Date: 2025-04-04
End Date: 2026-07-30
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

20

Intervention / Treatment

Red Light (PDT)

Placebo

Sponsor

University of Delaware

Source: clinicaltrials.gov

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A Study to Evaluate Investigational Agents With or Without Pembrolizumab (MK-3475) in Participants With Advanced Esophageal Cancer Previously Exposed to Programmed Cell Death 1 Protein (PD-1)/ Programmed Cell Death Ligand 1 (PD-L1) Treatment (MK-3475-06B)

Study ID: NCT05319730
Start Date: 2023-05-16
End Date: 2029-04-10
Study Type

Interventional

Study Phase

Phase2

No. of Participants

230

Intervention / Treatment

Paclitaxel

Irinotecan

Pembrolizumab

MK-4830

Lenvatinib

Sacituzumab tirumotecan

Antihistamine

H2 Receptor Antagonist

Acetaminophen (or equivalent)

Dexamethasone (or equivalent)

Steroid Mouthwash (dexamethasone or equivalent)

Supportive care measures

Sponsor

Merck Sharp & Dohme LLC

Source: clinicaltrials.gov

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Genetics and Aerobic Exercise to Slow Parkinson's Disease Trial

Study ID: NCT06442033
Start Date: 2024-08-23
End Date: 2028-12-31
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

200

Intervention / Treatment

High intensity stationary cycling

Sponsor

Jay Alberts

Source: clinicaltrials.gov

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