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Clinical trials for Parkinson Disease in United States

254 results

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Neuroimaging of Parkinson's

Study ID: NCT07024875
Start Date: 2025-08-01
End Date: 2031-01
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

120

Intervention / Treatment
Sponsor

Washington University School of Medicine

Source: clinicaltrials.gov

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Periodization and Parkinson's Disease

Study ID: NCT07141849
Start Date: 2025-08-29
End Date: 2025-12-30
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

60

Intervention / Treatment

Power Resistance Training

Periodized Resistance Training

Sponsor

University of Miami

Source: clinicaltrials.gov

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CPAP for the Treatment of Supine Hypertension

Study ID: NCT05489575
Start Date: 2022-06-23
End Date: 2026-08-31
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

59

Intervention / Treatment

Active CPAP

Sham CPAP

Sleeping in a head-up tilt (HUT) position

Sponsor

Vanderbilt University Medical Center

Source: clinicaltrials.gov

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A Study to Evaluate Investigational Agents With or Without Pembrolizumab (MK-3475) in Participants With Advanced Esophageal Cancer Previously Exposed to Programmed Cell Death 1 Protein (PD-1)/ Programmed Cell Death Ligand 1 (PD-L1) Treatment (MK-3475-06B)

Study ID: NCT05319730
Start Date: 2023-05-16
End Date: 2029-04-10
Study Type

Interventional

Study Phase

Phase2

No. of Participants

230

Intervention / Treatment

Paclitaxel

Irinotecan

Pembrolizumab

MK-4830

Lenvatinib

Sacituzumab tirumotecan

Antihistamine

H2 Receptor Antagonist

Acetaminophen (or equivalent)

Dexamethasone (or equivalent)

Steroid Mouthwash (dexamethasone or equivalent)

Supportive care measures

Sponsor

Merck Sharp & Dohme LLC

Source: clinicaltrials.gov

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Speech Learning and Speech Production in Parkinson's Disease

Study ID: NCT07403539
Start Date: 2026-01-27
End Date: 2027-12-31
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

50

Intervention / Treatment

Intensity learning

Intensity discrimination

Rate learning

Rate discrimination

Sponsor

State University of New York at Buffalo

Source: clinicaltrials.gov

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Physiological Brain Atlas Development

Study ID: NCT00575081
Start Date: 2006-08
End Date: 2026-08
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

5000

Intervention / Treatment

Stereotactic brain procedures

Sponsor

Vanderbilt University Medical Center

Source: clinicaltrials.gov

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A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) as First-line Maintenance Treatment of Cervical Cancer (MK-2870-036/TroFuse-036/GOG-3123/ENGOT-cx22)

Study ID: NCT07216703
Start Date: 2026-01-19
End Date: 2031-10-29
Study Type

Interventional

Study Phase

Phase3

No. of Participants

1023

Intervention / Treatment

Pembrolizumab

Sacituzumab Tirumotecan

bevacizumab

Paclitaxel

Cisplatin

Carboplatin

Rescue Medications

Sponsor

Merck Sharp & Dohme LLC

Source: clinicaltrials.gov

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Adaptive Neurostimulation to Restore Sleep in Parkinson's Disease (Aim 2)

Study ID: NCT05070013
Start Date: 2021-11-18
End Date: 2026-06-30
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

20

Intervention / Treatment

Deep Brain Stimulation

Sponsor

University of Nebraska

Source: clinicaltrials.gov

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Early Longitudinal Imaging in the Parkinson's Progressive Marker Initiative (PPMI) Using (18F)AV-133 (PPMI AV-133 Prodromal Imaging)

Study ID: NCT07265596
Start Date: 2023-10-30
End Date: 2027-12
Study Type

Interventional

Study Phase

Phase2

No. of Participants

100

Intervention / Treatment

[18F] AV-133 PET Imaging

Sponsor

Michael J. Fox Foundation for Parkinson's Research

Source: clinicaltrials.gov

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Cognitive Decline Following Deep Brain Stimulation: A DBS-fMRI Study

Study ID: NCT06960096
Start Date: 2025-08-21
End Date: 2028-04-01
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

55

Intervention / Treatment

DBS combined with fMRI

Sponsor

Medical University of South Carolina

Source: clinicaltrials.gov

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