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Clinical trials for Cancer in United States

7934 results

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Talazoparib and Low-Dose Temozolomide in Treating Participants With Relapsed or Refractory Extensive-Stage Small Cell Lung Cancer

Study ID: NCT03672773
Start Date: 2018-10-31
End Date: 2026-10-01
Study Type

Interventional

Study Phase

Phase2

No. of Participants

28

Intervention / Treatment

Carcolor

Temozolomide

Sponsor

Jonsson Comprehensive Cancer Center

Source: clinicaltrials.gov

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Phase I Study of Tumor Treating Fields (TTF) in Combination With Cabozantinib or With Pembrolizumab and Nab-Paclitaxel in Patients With Advanced Solid Tumors Involving the Abdomen or Thorax

Study ID: NCT05092373
Start Date: 2022-04-29
End Date: 2026-09-01
Study Type

Interventional

Study Phase

Phase1

No. of Participants

43

Intervention / Treatment

Atezolizumab

Cabozantinib S-malate

Nab-paclitaxel

Tumor Treating Fields Therapy

Sponsor

M.D. Anderson Cancer Center

Source: clinicaltrials.gov

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JNJ-90301900 (NBTXR3) Activated by Radiotherapy With or Without Cetuximab in LA-HNSCC

Study ID: NCT04892173
Start Date: 2021-12-10
End Date: 2027-06-30
Study Type

Interventional

Study Phase

Phase3

No. of Participants

500

Intervention / Treatment

JNJ-90301900 (NBTXR3)

Cetuximab

Radiation Therapy

Sponsor

Johnson & Johnson Enterprise Innovation Inc.

Source: clinicaltrials.gov

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Immune Cell Therapy (CAR-T) for the Treatment of Patients With HIV and B-Cell Non-Hodgkin Lymphoma

Study ID: NCT05077527
Start Date: 2024-05-03
End Date: 2027-01-31
Study Type

Interventional

Study Phase

Phase1

No. of Participants

20

Intervention / Treatment

Axicabtagene Ciloleucel

Cyclophosphamide

Fludarabine

Sponsor

AIDS Malignancy Consortium

Source: clinicaltrials.gov

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Myeloablative Conditioning Orca-T & Allogeneic Donor-Derived CD19/CD22-CAR TCells in B-Cell ALL

Study ID: NCT05507827
Start Date: 2022-08-18
End Date: 2037-01
Study Type

Interventional

Study Phase

Phase1

No. of Participants

18

Intervention / Treatment

Allogeneic donor-derived T-cells transduced with bivalent lentiviral vector (CD19/CD22-BBz) chimeric antigen receptor (CAR)

Treg CD34+HSPC (Orca-T)

Sponsor

Melody Smith

Source: clinicaltrials.gov

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EpiDetect Study: Clinical Validation of a Pancreatic Cancer Detection Test in New-Onset Diabetes Patients

Study ID: NCT05188573
Start Date: 2022-06-01
End Date: 2025-05-31
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

10000

Intervention / Treatment

Early detection pancreatic cancer test

Early detection pancreatic cancer test and MRI Imaging

Sponsor

ClearNote Health

Source: clinicaltrials.gov

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Phase I/II Trial in ES-SCLC to Enhance Response to Atezolizumab Plus Chemotherapy With Total Body Irradiation

Study ID: NCT06110572
Start Date: 2024-04-24
End Date: 2028-06-30
Study Type

Interventional

Study Phase

Phase2

No. of Participants

18

Intervention / Treatment

Carboplatin

Atezolizumab

Etoposide

Total Body Irradiation

Hypofractionated Radiation Therapy

Magnetic Resonance Imaging

Sponsor

Vanderbilt-Ingram Cancer Center

Source: clinicaltrials.gov

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Addition of Antibiotics to Upfront Treatment Regimen for Colorectal Cancer

Study ID: NCT06728072
Start Date: 2025-03-07
End Date: 2035-07-01
Study Type

Interventional

Study Phase

Phase2

No. of Participants

97

Intervention / Treatment

Standard of Care Chemotherapy + Metronidazole, ciprofloxacin, aspirin

Sponsor

Virginia Commonwealth University

Source: clinicaltrials.gov

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Testing the Combination of APG-1252 (Pelcitoclax) and Cobimetinib in Recurrent Ovarian and Endometrial Cancers

Study ID: NCT05691504
Start Date: 2023-09-14
End Date: 2027-02-01
Study Type

Interventional

Study Phase

Phase1

No. of Participants

42

Intervention / Treatment

Biopsy Procedure

Biospecimen Collection

Cobiet

Computed Tomography

Echocardiography Test

Magnetic Resonance Imaging

Multigated Acquisition Scan

Pelcitoclax

Sponsor

National Cancer Institute (NCI)

Source: clinicaltrials.gov

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Study of 68Ga-R10602

Study ID: NCT06745804
Start Date: 2024-12-10
End Date: 2025-12
Study Type

Interventional

Study Phase

Phase1

No. of Participants

22

Intervention / Treatment

68Ga-R10602 injection

Sponsor

Radionetics Oncology

Source: clinicaltrials.gov

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