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Clinical trials for Cancer in United States

7251 results

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Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

Study ID: NCT04181060
Start Date: 2020-12-28
End Date: 2026-12-31
Study Type

Interventional

Study Phase

Phase3

No. of Participants

300

Intervention / Treatment

Infatuating

Biospecimen Collection

Computed Tomography

Echocardiography Test

Magnetic Resonance Imaging

Multigated Acquisition Scan

Osimertinib

Sponsor

National Cancer Institute (NCI)

Source: clinicaltrials.gov

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Study of ISM3412 in Participants With Locally Advanced/Metastatic Solid Tumors

Study ID: NCT06414460
Start Date: 2025-04-25
End Date: 2029-03-31
Study Type

Interventional

Study Phase

Phase1

No. of Participants

80

Intervention / Treatment

ISM3412

Sponsor

InSilico Medicine Hong Kong Limited

Source: clinicaltrials.gov

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Collection and Storage of Tissue and Blood Samples From Patients With Cancer

Study ID: NCT02474160
Start Date: 2015-05-19
End Date: 2026-05-04
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

5000

Intervention / Treatment

Cytology Specimen Collection Procedure

Sponsor

National Cancer Institute LAO

Source: clinicaltrials.gov

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Mosunetuzumab With Chemotherapy for the Treatment of Patients With Untreated C-Myc Rearrangement Positive High Grade B Cell Lymphoma or Diffuse Large B Cell Lymphoma

Study ID: NCT06249191
Start Date: 2024-06-13
End Date: 2027-04-01
Study Type

Interventional

Study Phase

Phase2

No. of Participants

30

Intervention / Treatment

Biopsy

Biospecimen Collection

Bone Marrow Aspiration and Biopsy

Computed Tomography

Cyclophosphamide

Doxorubicin

Echocardiography

Etoposide

Magnetic Resonance Imaging

Mosunetuzumab

Multigated Acquisition Scan

Positron Emission Tomography

Prednisone

Vincristine

Sponsor

OHSU Knight Cancer Institute

Source: clinicaltrials.gov

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A Study of the Use of Fat Flap Reconstruction to Reduce Neck Injury After Cancer Treatment

Study ID: NCT05889091
Start Date: 2023-05-16
End Date: 2026-05-16
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

12

Intervention / Treatment

HRQOL instruments

LENT SOMA instrument

Sponsor

Memorial Sloan Kettering Cancer Center

Source: clinicaltrials.gov

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Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of GS-9716 as Monotherapy and in Combination With Anticancer Therapies in Adults With Solid Malignancies

Study ID: NCT05006794
Start Date: 2021-09-15
End Date: 2029-03
Study Type

Interventional

Study Phase

Phase1

No. of Participants

145

Intervention / Treatment

zamzetoclax

Docetaxel

sacituzumab Govitan-Hzius

Sponsor

Gilead Sciences

Source: clinicaltrials.gov

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Intracerebroventricular Administration of CD19-CAR T Cells (CD19CAR-CD28-CD3zeta-EGFRt-expressing Tcm-enriched T-lymphocytes) for the Treatment of Primary Central Nervous System Lymphoma

Study ID: NCT05625594
Start Date: 2023-06-29
End Date: 2026-05-21
Study Type

Interventional

Study Phase

Phase1

No. of Participants

20

Intervention / Treatment

Aspiration

Biospecimen Collection

Catheterization

CD19CAR-CD28-CD3zeta-EGFRt-expressing Tcm-enriched T-lymphocytes

Computed Tomography

Cyclophosphamide

Fludarabine

Leukapheresis

Lumbar Puncture

Magnetic Resonance Imaging

Positron Emission Tomography

Sponsor

City of Hope Medical Center

Source: clinicaltrials.gov

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A Study to Assess Safety and Efficacy of SOT201 in Patients With Advanced/Metastatic Cancer

Study ID: NCT06163391
Start Date: 2024-05-01
End Date: 2026-10
Study Type

Interventional

Study Phase

Phase1

No. of Participants

40

Intervention / Treatment

SOT201

Sponsor

Saidio biotech ag

Source: clinicaltrials.gov

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Molecular Analysis of Samples From Patients With Diffuse Intrinsic Pontine Glioma and Brainstem Glioma

Study ID: NCT01106794
Start Date: 2010-04
End Date: 2030-04
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

100

Intervention / Treatment
Sponsor

Children's National Research Institute

Source: clinicaltrials.gov

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A Study to Evaluate the Safety and Efficacy of Pembrolizumab (MK-3475) Coformulated With Berahyaluronidase Alfa (MK-3475A) in Participants With Relapsed or Refractory Classical Hodgkin Lymphoma (rrcHL) or Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma (rrPMBCL)(MK-3475A-F65)

Study ID: NCT06504394
Start Date: 2024-10-14
End Date: 2028-11-08
Study Type

Interventional

Study Phase

Phase2

No. of Participants

60

Intervention / Treatment

Pembrolizumab (+) Berahyaluronidase alfa

Sponsor

Merck Sharp & Dohme LLC

Source: clinicaltrials.gov

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