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Clinical trials for Cancer in United States

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Oral Axl/Mer/CSF1R Selective Tyrosine Kinase Inhibitor Q702 in Combination With Pembrolizumab in Patients With Selected Advanced Solid Tumors

Study ID: NCT05438420
Start Date: 2023-01-12
End Date: 2026-06-30
Study Type

Interventional

Study Phase

Phase2

No. of Participants

120

Intervention / Treatment

Q702

Pembrolizumab

Sponsor

Qurient Co., Ltd.

Source: clinicaltrials.gov

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Use of Serial Plasma NGS as a New Efficacy Metric to Guide Immunotherapy Treatment Discontinuation

Study ID: NCT06146920
Start Date: 2024-01-10
End Date: 2028-11
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

39

Intervention / Treatment

Evaluation of ctDNA using the F1T after 1 year of immunotherapy

Sponsor

Massachusetts General Hospital

Source: clinicaltrials.gov

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SRS Compared with FSRS for Treatment of Intact Metastatic Brain Disease, FRACTIONATE Trial

Study ID: NCT05222620
Start Date: 2022-03-14
End Date: 2028-02-15
Study Type

Interventional

Study Phase

Phase2

No. of Participants

69

Intervention / Treatment

Administration questionnaire

Stereotactic Radiosurgery

Stereotactic Radiosurgery

Magnetic Resonance Imaging

Sponsor

Mayo Clinic

Source: clinicaltrials.gov

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Acolbifene Versus Low Dose Tamoxifen for the Prevention of Breast Cancer in Premenopausal Women at High Risk for Development of Breast Cancer

Study ID: NCT05941520
Start Date: 2024-08-23
End Date: 2028-09-01
Study Type

Interventional

Study Phase

Phase2

No. of Participants

80

Intervention / Treatment

Acolbifene Hydrochloride

Biospecimen Collection

Mammography

Administration questionnaire

Random Periareolar Fine-Needle Aspiration

Ta grinding powder

Sponsor

National Cancer Institute (NCI)

Source: clinicaltrials.gov

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Comparing Retreatment of 177Lu-DOTATATE PRRT Versus Everolimus in Patients With Metastatic Unresectable Midgut Neuroendocrine Tumors, NET RETREAT Trial

Study ID: NCT05773274
Start Date: 2024-01-12
End Date: 2026-04-30
Study Type

Interventional

Study Phase

Phase2

No. of Participants

100

Intervention / Treatment

Biospecimen Collection

Computed Tomography

Everolimus

Lutetium Lu 177 dotatate

Quality-of-Life Assessment

Administration questionnaire

Sponsor

National Cancer Institute (NCI)

Source: clinicaltrials.gov

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Bladder Cancer Longitudinal Biorepository for Development of Novel Therapeutics/Biomarkers

Study ID: NCT03413982
Start Date: 2017-11-02
End Date: 2035-01-01
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

1000

Intervention / Treatment

Registry

Sponsor

University of Kansas Medical Center

Source: clinicaltrials.gov

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A Phase II Study of the Combination of Pembrolizumab and ATRA Combination Treatment of Relapsed HL and B-NHL

Study ID: NCT06484920
Start Date: 2024-11-18
End Date: 2029-09
Study Type

Interventional

Study Phase

Phase2

No. of Participants

24

Intervention / Treatment

ATRA

Pembrolizumab

Sponsor

Rita Assi

Source: clinicaltrials.gov

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Maternal Cancer Diagnosis and Treatment During Pregnancy:a Database for Maternal, Fetal, and Neonatal Outcomes

Study ID: NCT02749474
Start Date: 2003-07
End Date: 2025-07
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

400

Intervention / Treatment
Sponsor

The Cooper Health System

Source: clinicaltrials.gov

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CER-1236 in Patients With Acute Myeloid Leukemia (AML)

Study ID: NCT06834282
Start Date: 2025-04-07
End Date: 2029-12-31
Study Type

Interventional

Study Phase

Phase1

No. of Participants

18

Intervention / Treatment

CER-1236

Cyclophosphamide

Fludarabine

Meat

Sponsor

CERo Therapeutics Holdings, Inc.

Source: clinicaltrials.gov

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EUS Examination Using EndoSound Vision System vs. Standard Echoendoscope

Study ID: NCT06340620
Start Date: 2024-03-25
End Date: 2027-12
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

140

Intervention / Treatment

Endoscopic ultrasound examination

Sponsor

Orlando Health, Inc.

Source: clinicaltrials.gov

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