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Clinical trials for Cancer in United States

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A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

Study ID: NCT06051695
Start Date: 2024-04-03
End Date: 2029-06
Study Type

Interventional

Study Phase

Phase2

No. of Participants

474

Intervention / Treatment

Abatas 4

43

xT CDx with HLA-LOH Assay

Sponsor

A2 Biotherapeutics Inc.

Source: clinicaltrials.gov

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Symptoms of Immune Checkpoint Inhibitor Therapy in Cutaneous Melanoma

Study ID: NCT07148245
Start Date: 2025-10-13
End Date: 2027-06-30
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

300

Intervention / Treatment

Blood Sample

Health Related Quality of Life Questionnaires (HRQoL)

Medical Chart Review

Sponsor

University of California, San Francisco

Source: clinicaltrials.gov

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Characterization of 18F-Fluciclovine PET Amino Acid Radiotracer in Resected Brain Metastasis

Study ID: NCT05554302
Start Date: 2023-01-10
End Date: 2030-01
Study Type

Interventional

Study Phase

Phase2

No. of Participants

20

Intervention / Treatment

18F-Fluciclovine

Sponsor

Baptist Health South Florida

Source: clinicaltrials.gov

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Observational Study of Women With Endometrial Cancer Who Receive the Standard Treatment for Their Disease

Study ID: NCT04291612
Start Date: 2020-02-26
End Date: 2026-02-26
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

1715

Intervention / Treatment

Physical exam

Sponsor

Memorial Sloan Kettering Cancer Center

Source: clinicaltrials.gov

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The COMPASSION Study

Study ID: NCT06507930
Start Date: 2024-09-01
End Date: 2027-03-01
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

200

Intervention / Treatment

Telehealth Hospice Visits

Sponsor

Dana-Farber Cancer Institute

Source: clinicaltrials.gov

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The Efficacy of Conventional Screening Versus mHealth Screening in Early Detection of Oral Potentially Malignant Disorders and Oral Cancer Amongst the Rural Population of Varanasi: A Prospective and Blinded Study

Study ID: NCT06535867
Start Date: 2024-07-30
End Date: 2031-07-30
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

5122

Intervention / Treatment

mHealth

Sponsor

Memorial Sloan Kettering Cancer Center

Source: clinicaltrials.gov

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Cord Blood Transplant in Children and Young Adults With Blood Cancers and Non-malignant Disorders

Study ID: NCT04644016
Start Date: 2020-11-20
End Date: 2025-12-20
Study Type

Interventional

Study Phase

Phase2

No. of Participants

31

Intervention / Treatment

Clofarabine

Fludarabine

Busulfan

Cyclosporine-A

Mycophenolate Mofetil

Cord Blood Graft

Sponsor

Memorial Sloan Kettering Cancer Center

Source: clinicaltrials.gov

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Neoadjuvant Targeting of Myeloid Cell Populations in Combination With Nivolumab in Head & Neck Ca

Study ID: NCT04848116
Start Date: 2021-04-24
End Date: 2026-09
Study Type

Interventional

Study Phase

Phase2

No. of Participants

24

Intervention / Treatment

Nivolumab

HuMax-IL8

Sponsor

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Source: clinicaltrials.gov

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Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer

Study ID: NCT06890598
Start Date: 2025-03-27
End Date: 2032-02
Study Type

Interventional

Study Phase

Phase3

No. of Participants

700

Intervention / Treatment

Olomorasib

Pembrolizumab

Durvalumab

Placebo

Sponsor

Eli Lilly and Company

Source: clinicaltrials.gov

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A Study to Evaluate the Safety and Efficacy of BGB-16673 Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Study ID: NCT06973187
Start Date: 2025-09-04
End Date: 2028-04-17
Study Type

Interventional

Study Phase

Phase3

No. of Participants

500

Intervention / Treatment

BGB-16673

Pirtobrutinib

Sponsor

BeOne Medicines

Source: clinicaltrials.gov

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