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Clinical trials for Cancer in United States

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DNA-guided Second Line Adjuvant Therapy for High Residual Risk, Estrogen Receptor Positive, HER-2 Negative Breast Cancer (DARE)

Study ID: NCT04567420
Start Date: 2021-02-09
End Date: 2027-12-31
Study Type

Interventional

Study Phase

Phase2

No. of Participants

70

Intervention / Treatment

Palbociclib

Fulvestrant

Adjuvant Therapy

Sponsor

Criterium, Inc.

Source: clinicaltrials.gov

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Collection of Specimens and Clinical Data for Patients With Recurrent or Metastatic Breast Cancer or Male Breast Cancer

Study ID: NCT06217874
Start Date: 2014-06-05
End Date: 2034-06-30
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

5000

Intervention / Treatment

Non-Interventional Study

Sponsor

Mayo Clinic

Source: clinicaltrials.gov

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International Rare Brain Tumor Registry

Study ID: NCT05697874
Start Date: 2023-01-01
End Date: 2033-12
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

5800

Intervention / Treatment
Sponsor

Children's National Research Institute

Source: clinicaltrials.gov

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Meaning-Centered Pain Coping Skills Training for Cancer Pain

Study ID: NCT05385965
Start Date: 2023-02-09
End Date: 2026-03-26
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

210

Intervention / Treatment

Meaning-Centered Pain Coping Skills Training

Sponsor

Duke University

Source: clinicaltrials.gov

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LV20.19 CAR T-Cells in Combination With Pirtobrutinib for Relapsed, Refractory B-cell Malignancies

Study ID: NCT05990465
Start Date: 2025-02-06
End Date: 2027-07
Study Type

Interventional

Study Phase

Phase1

No. of Participants

12

Intervention / Treatment

Pester

LV20.19 CAR T cells

Sponsor

Medical College of Wisconsin

Source: clinicaltrials.gov

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First-in-Human Study of ATX-295, an Oral Inhibitor of KIF18A, in Patients With Advanced or Metastatic Solid Tumors, Including Ovarian Cancer

Study ID: NCT06799065
Start Date: 2025-03-21
End Date: 2027-08-30
Study Type

Interventional

Study Phase

Phase1

No. of Participants

65

Intervention / Treatment

ATX-295

Sponsor

Accent Therapeutics

Source: clinicaltrials.gov

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A Trial of AMXI-5001 for Treatment in Patients With Advanced Malignancies

Study ID: NCT04503265
Start Date: 2020-08-12
End Date: 2026-10
Study Type

Interventional

Study Phase

Phase2

No. of Participants

122

Intervention / Treatment

AMXI-5001:Dose Escalation Phase I

AMXI-5001:Dose Expansion Phase II

Sponsor

AtlasMedx, Incorporated

Source: clinicaltrials.gov

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A Study of AAV2-hAQP1 Gene Therapy in Participants With Radiation-Induced Late Xerostomia

Study ID: NCT05926765
Start Date: 2023-06-13
End Date: 2025-07
Study Type

Interventional

Study Phase

Phase2

No. of Participants

120

Intervention / Treatment

AAV2-hAQP1 Concentration 1

AAV2-hAQP1 Concentration 2

Placebo

Sponsor

MeiraGTx, LLC

Source: clinicaltrials.gov

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Anti-pneumococcal Vaccine Strategy in Patients with Chronic Lymphocytic Leukemia

Study ID: NCT05417165
Start Date: 2023-09-29
End Date: 2025-12-31
Study Type

Interventional

Study Phase

Phase2

No. of Participants

80

Intervention / Treatment

Pneumococcal 20-valent Conjugate Vaccine

Pneumococcal Polyvalent Vaccine

Sponsor

Seema Bhat

Source: clinicaltrials.gov

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Ovarian-Sparing Adaptive Radiotherapy in Young Adult Women

Study ID: NCT06904365
Start Date: 2025-04-08
End Date: 2026-04-15
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

10

Intervention / Treatment

HyperSight cone beam computed tomography (CBCT) scan

ETHOS 2.0

Sponsor

Washington University School of Medicine

Source: clinicaltrials.gov

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