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Clinical trials for Cancer in United States

7243 results

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Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors

Study ID: NCT06218914
Start Date: 2024-04-04
End Date: 2044-04-15
Study Type

Interventional

Study Phase

Phase1

No. of Participants

24

Intervention / Treatment

NT-112: Autologous, engineered T Cells targeting KRAS G12D

AZD0240: Autologous, engineered T Cells targeting KRAS G12D

Sponsor

AstraZeneca

Source: clinicaltrials.gov

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Observational Study of Women With Endometrial Cancer Who Receive the Standard Treatment for Their Disease

Study ID: NCT04291612
Start Date: 2020-02-26
End Date: 2026-02-26
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

1400

Intervention / Treatment

Physical exam

Sponsor

Memorial Sloan Kettering Cancer Center

Source: clinicaltrials.gov

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Multicenter Study of Seliciclib (R-roscovitine) for Cushing Disease

Study ID: NCT03774446
Start Date: 2018-11-02
End Date: 2025-08
Study Type

Interventional

Study Phase

Phase2

No. of Participants

13

Intervention / Treatment

Seliciclib

Sponsor

Cedars-Sinai Medical Center

Source: clinicaltrials.gov

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Head and Neck Cancer Patient Symptom and Oncologic Outcomes

Study ID: NCT05243069
Start Date: 2023-03-31
End Date: 2028-12-31
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

80

Intervention / Treatment

Imaging Technique

Sponsor

Ohio State University Comprehensive Cancer Center

Source: clinicaltrials.gov

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Support Through Remote Observation and Nutrition Guidance Program for Individuals With Gastroesophageal Cancer

Study ID: NCT06497569
Start Date: 2024-07-26
End Date: 2027-06
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

80

Intervention / Treatment

Dietitian Consultation

Survey

Fitbit Data Collection

Referral to Dietitian

Social Determinants of Health Survey (SDOH)

Sponsor

H. Lee Moffitt Cancer Center and Research Institute

Source: clinicaltrials.gov

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Total Marrow and Lymphoid Irradiation, Fludarabine, and Melphalan Before Donor Stem Cell Transplant in Treating Participants With High-Risk Acute Leukemia or Myelodysplastic Syndrome

Study ID: NCT03494569
Start Date: 2018-07-06
End Date: 2025-10-11
Study Type

Interventional

Study Phase

Phase1

No. of Participants

36

Intervention / Treatment

Fludarabine

Laboratory Biomarker Analysis

Melphalan

Total Marrow Irradiation

Sponsor

City of Hope Medical Center

Source: clinicaltrials.gov

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Adaptive Radiation Therapy (ART) Stereotactic Ablative Body Radiotherapy (SABR) for Primary Localized Prostate Cancer

Study ID: NCT06325046
Start Date: 2024-08-15
End Date: 2026-08
Study Type

Interventional

Study Phase

Not Applicable

No. of Participants

144

Intervention / Treatment

Computed Tomography

Cone-Beam Computed Tomography

Image-Guided Adaptive Radiation Therapy

Magnetic Resonance Imaging

Stereotactic Ablative Radiotherapy

Survey Administration

Sponsor

Mayo Clinic

Source: clinicaltrials.gov

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JAB-30355 in Patients With Advanced Solid Tumors Harboring TP53 Y220C Mutation

Study ID: NCT06386146
Start Date: 2024-07-24
End Date: 2027-07
Study Type

Interventional

Study Phase

Phase2

No. of Participants

144

Intervention / Treatment

JAB-30355

JAB-30355

Sponsor

Jacobio Pharmaceuticals Co., Ltd.

Source: clinicaltrials.gov

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Registry to Collect Data on Patients Undergoing Segmental Mandibular Defect Reconstruction Following Oral Squamous Cell Carcinoma Resection and Drugs-induced Osteonecrosis

Study ID: NCT04098146
Start Date: 2022-09-12
End Date: 2030-12-31
Study Type

Observational

Study Phase

Not Applicable

No. of Participants

300

Intervention / Treatment

Surgical Resection and Reconstruction

Sponsor

AO Innovation Translation Center

Source: clinicaltrials.gov

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Immunotherapy Before and After Surgery for Treatment of Recurrent or Progressive High Grade Glioma in Children and Young Adults

Study ID: NCT04323046
Start Date: 2020-10-02
End Date: 2029-03-01
Study Type

Interventional

Study Phase

Phase1

No. of Participants

20

Intervention / Treatment

Nivolumab

Quality-of-Life Assessment

Administration questionnaire

Sponsor

Sabine Mueller, MD, PhD

Source: clinicaltrials.gov

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