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NCT07403188 | RECRUITING | Refractory Lupus Nephritis


A Long-Term Follow-Up Study for Participants Previously Treated With KYV-101
Sponsor:

It governs Therapeutics

Brief Summary:

The purpose of this long-term follow-up (LTFU) study is to collect delayed adverse events (AEs) and understand the persistence of KYV-101 (autologous CAR T cell product; gene-modified product), in participants who have been administered KYV-101 (gene-modified product; autologous CAR T cell product). This LTFU protocol will be open to any participant who received at least one infusion of KYV-101 in a previous Kyverna sponsored clinical trial or Investigator Initiated Trial (IIT).

Condition or disease

Refractory Lupus Nephritis

Myasthaenia Gravis

Stiff Person Syndrome

Rheumatoid Arthritis (RA)

Multiple Sclerosis

Dermatomyositis

Systemic Sclerosis (SSc)

Intervention/treatment

KYV-101

Study Type : OBSERVATIONAL
Estimated Enrollment : 70 participants
Official Title : A Long-Term Follow-Up Study for Participants Previously Treated With KYV-101
Actual Study Start Date : 2025-11-24
Estimated Primary Completion Date : 2041-01
Estimated Study Completion Date : 2041-01

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • * Provided informed consent for the LTFU study
  • * Received at least 1 infusion of KYV-101 as part of a previous KYV-101 parent treatment protocol
Exclusion Criteria
  • * Not applicable

A Long-Term Follow-Up Study for Participants Previously Treated With KYV-101

Location Details

NCT07403188


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How to Participate

Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.

Locations


RECRUITING

United States, Colorado

University of Colorado, Denver

Denver, Colorado, United States, 80045

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