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NCT07065747 | RECRUITING | Anterior Uveitis (AU)

Quantification & Classification of Inflammatory Cells in Uveitis Using OCT
Sponsor:

Oregon Health and Science University

Information provided by (Responsible Party):

David Huang

Brief Summary:

The goal of this study is to determine if it's possible to use a high resolution imaging device called optical coherence tomography (OCT) to develop an unbiased, standard method of counting and categorizing the various types of cells and proteins found in an eye condition called anterior uveitis. Anterior uveitis is a type of inflammation in the eye that can be caused by many different diseases of the body.

Condition or disease

Anterior Uveitis (AU)

Birdshot Chorioretinitis

Behcet Disease

Herpes Simplex Virus

Juvenile Idiopathic Arthritis (JIA)

Spondyloarthritis (SA)

Sarcoidosis

Posterior Vitreous Detachment

Study Type : OBSERVATIONAL
Estimated Enrollment : 125 participants
Official Title : Objective Grading of Intraocular Inflammation in Uveitis Using Optical Coherence Tomography
Actual Study Start Date : 2024-09-01
Estimated Primary Completion Date : 2026-09
Estimated Study Completion Date : 2026-12

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 5 Years to 85 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: 1
Criteria
Inclusion Criteria
  • 1. Uveitis Group: Eyes with active intraocular inflammation and a clinical diagnose of spondyloarthritis/HLA-B27 associated anterior uveitis, Juvenile Idiopathic Arthritis (JIA) associated chronic anterior uveitis, Herpes Simplex Virus (HSV) anterior uveitis, Birdshot chorioretinitis, Behcet disease uveitis, sarcoidosis associated uveitis, uveitis of any additional type, or uveitis masquerade.
  • 2. Posterior Vitreous Detachment Group: Eyes with vitreous floaters and posterior vitreous detachment (PVD).
  • 3. Healthy/Control Group: Healthy eyes with no history of uveitis, PVD, or previous eye surgery.
Exclusion Criteria
  • 1. Inability to give informed consent.
  • 2. Inability to maintain stable fixation for OCT imaging.
  • 3. Inability to commit to required visits to complete the study.
  • 4. Pregnancy and breastfeeding.
Quantification & Classification of Inflammatory Cells in Uveitis Using OCT

Location Details

NCT07065747

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How to Participate

Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.

Locations

RECRUITING

United States, Oregon

Casey Eye Institute - Oregon Health & Science University

Portland, Oregon, United States, 97239