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NCT07011862 | RECRUITING | Primary Cancer

COBRA: Cancer, Older Adults, Balance and Resistance Activities
Sponsor:

Memorial Sloan Kettering Cancer Center

Brief Summary:

The purpose of this study is to find out whether an 8-week digital health promotion program called COBRA is a safe and practical (feasible) option for older adults with cancer/OAC.

Condition or disease

Primary Cancer

Metastatic Cancer

Cancer

Intervention/treatment

Cancer, Older adults, Balance and Resistance Activities

Phase

NA

Study Type : INTERVENTIONAL
Estimated Enrollment : 38 participants
Masking : NONE
Primary Purpose : SUPPORTIVE_CARE
Official Title : COBRA: Cancer, Older Adults, Balance and Resistance Activities
Actual Study Start Date : 2025-05-30
Estimated Primary Completion Date : 2027-05-30
Estimated Study Completion Date : 2027-05-30

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 65 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • Older Adult Patients with Cancer
  • - Are within 1 year of completion of primary therapy for cancer OR have a diagnosis of metastatic cancer;
  • 1. For the purpose of this study, primary therapy is defined as treatment of curative intent, first-line or later, from which the individual is advancing to active surveillance or follow-up with or without maintenance therapy.
  • 2. Individuals with metastatic cancer may be included provided they have stable disease or better per most recent restaging exam at time of enrollment.
  • i. Patients with stable metastatic bony disease at most recent restaging exam and a score of 0-2 on the Functional Pain Scale (FPS69; Appendix 18) are eligible. The PI will consult with the Rehab Med co-PI for FPS scores of 3 or greater, by patient request or PI discretion.
  • ii. Patients with symptomatic visceral metastases will be evaluated on a case-by-case basis at time of enrollment.
  • * Are aged 65 years and older, with no upper age limit;
  • * ECOG PS 0-3 or Karnofsky PS greater than or equal to 40;
  • * Can read and speak English;
  • * Self-report access to internet connection sufficient to support videoconferencing.
  • Clinicians
  • * Licensed clinician (MD, RN, APP) with an interest in the care of older adults with cancer.
Exclusion Criteria
  • Older Adult Patients with Cancer
  • * Have any cognitive impairment, neurologic, musculoskeletal, or other comorbid condition (as assessed by their provider) that would prevent the individual from engaging with the digital health coaching program or complete study assessments or engage in progressive intensity levels of physical activity
  • * Have a neurologic, musculoskeletal, or other comorbid condition that would impede their ability to safely engage in progressive intensity levels of physical activity (as assessed by their provider). Patients with metastatic disease and suspected interim progression since last restaging exam will be referred back to their primary oncology care team for evaluation prior to enrollment.
  • * Have activity restrictions post-surgery at the time of enrollment
  • Clinicians No expected exclusions
COBRA: Cancer, Older Adults, Balance and Resistance Activities

Location Details

NCT07011862

Please Choose a site

How to Participate

Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.

Locations

RECRUITING

United States, New Jersey

Memorial Sloan Kettering Monmouth (Consent only)

Middletown, New Jersey, United States, 07748

RECRUITING

United States, New Jersey

Memorial Sloan Kettering Bergen (Consent Only)

Montvale, New Jersey, United States, 07645

RECRUITING

United States, New York

Memorial Sloan Kettering Suffolk-Commack (Consent Only)

Commack, New York, United States, 11725

RECRUITING

United States, New York

Memorial Sloan Kettering Westchester (Consent only)

Harrison, New York, United States, 10604

RECRUITING

United States, New York

Memorial Sloan Kettering Cancer Center (All Protocol Activites)

New York, New York, United States, 10065

RECRUITING

United States, New York

Memorial Sloan Kettering Nassau (Consent Only)

Uniondale, New York, United States, 11553