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NCT07003113 | RECRUITING | Low Back Pain

Ischemic Preconditioning in Osteoarthritis and Back Pain
Sponsor:

University of Illinois at Chicago

Brief Summary:

We are examining the use of restricted blood flow, through full occlusion, on a single thigh for 50 minutes (5 minutes on, 5 minutes off), completed every other day for 2 weeks to improve function in individuals with knee osteoarthritis and low back pain.

Condition or disease

Low Back Pain

Knee Osteoarthritis

Intervention/treatment

Ischemic Preconditioning

Sham Intervention

Phase

NA

Study Type : INTERVENTIONAL
Estimated Enrollment : 24 participants
Masking : SINGLE
Primary Purpose : TREATMENT
Official Title : Ischemic Preconditioning in Osteoarthritis and Back Pain
Actual Study Start Date : 2025-09-12
Estimated Primary Completion Date : 2026-07-31
Estimated Study Completion Date : 2026-12-31

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 50 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • * Reported Knee Pain using ACR Criteria
  • * Reported Back Pain using ODI Criteria \> 12
  • * Ability to walk for at least 3 minutes without the use of aids
  • * Ability to provide written informed consent
Exclusion Criteria
  • * Younger than 50 years old
  • * History of Knee or Hip Replacements
  • * History of steroid injection within the previous 6 months
  • * Presence of neuromuscular joint condition that affects lower extremity function
  • * History of blood clots in the leg or any condition in which compression of the thigh is contraindicated
  • * History of heart failure or thrombosis
  • * Allergic to ultrasound gel
  • * History of spine surgery
  • * Non-English speaker
  • * Currently pregnant or intends to become pregnant during the study
Ischemic Preconditioning in Osteoarthritis and Back Pain

Location Details

NCT07003113

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How to Participate

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Locations

RECRUITING

United States, Illinois

Human and Sport Performance Lab

Chicago, Illinois, United States, 60608