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NCT06930066 | NOT YET RECRUITING | Liver Stiffness


Normal Pediatric Liver and Spleen SWE
Sponsor:

Selcuk University

Information provided by (Responsible Party):

Mehmet Akif Ağır

Brief Summary:

This observational study aims to determine normal liver and spleen stiffness values in healthy children using shear wave elastography (SWE). The study will include participants from the pediatric age group without known liver or spleen disease. SWE measurements will be performed non-invasively to establish reference values. The results may contribute to improving diagnostic accuracy in pediatric elastography applications.

Condition or disease

Liver Stiffness

Spleen Stiffness

Shear Wave Elastography in Healthy Children

Normal Organ Elasticity

Pediatric Elastography

Detailed Description:

Shear wave elastography (SWE) is a non-invasive imaging method used to assess tissue stiffness. While reference values for SWE have been established in adults, data regarding normal liver and spleen stiffness in children are limited. This single-center, cross-sectional observational study aims to establish normative SWE values for the liver and spleen in the pediatric age group. Children with no known liver or spleen pathology will undergo standardized SWE measurement under controlled conditions. Age-specific and sex-specific reference ranges will be analyzed, which may contribute to enhancing the clinical utility of SWE in pediatric practice.

Study Type : OBSERVATIONAL
Estimated Enrollment : 450 participants
Official Title : Normal Liver and Spleen Stiffness Values Using Shear Wave Elastography in Children
Actual Study Start Date : 2025-04-30
Estimated Primary Completion Date : 2025-06-15
Estimated Study Completion Date : 2025-06-30

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 1 Month to 18 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: 1
Criteria
Inclusion Criteria
  • * Healthy children aged 0-18 years, with no known liver or spleen pathology. Participants must have written consent from their parents or guardians.
Exclusion Criteria
  • * Children with any known liver or spleen disease, including hepatitis, cirrhosis, splenomegaly, or any history of liver and spleen disease. Children outside the age range of 0-18 years.

Normal Pediatric Liver and Spleen SWE

Location Details

NCT06930066


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