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NCT06929494 | NOT YET RECRUITING | Sepsis


Candidemia in Critically Ill Patients
Sponsor:

Meir Medical Center

Information provided by (Responsible Party):

Sara Dichtwald

Brief Summary:

Candidal sepsis (candidemia) is a criticals problem in patients hospitalized in the intensive care unit, with a significant impact on morbidity and mortality. Risk factors for candidemia in intensive care patients included age, presence of a central venous catheter, inpatient surgery, and administration of parenteral nutrition (TPN). Mortality in patients with candidemia is estimated at 50-60%. Early identification and treatment, including control of the source of infection, are essential to improve morbidity and mortality in these patients. In this study, we would like to identify risk factors for the development of candidemia in intensive care patients, including those who have not undergone abdominal surgery, and to examine what percentage of patients who developed candidemia were given empirical antifungal therapy and what factors influenced the decision to give or not to give such empirical therapy. Study design: A retrospective study based on data collection from computerized systems will include patients who were hospitalized in the intensive care unit from January 2014 to December 2024 and were diagnosed with Candida in at least one blood culture.

Condition or disease

Sepsis

Intervention/treatment

Identification of risk factors for candidemia

Study Type : OBSERVATIONAL
Estimated Enrollment : 70 participants
Official Title : Candidemia in Critically Ill Patients: Risk Factors and Predictive Factors
Actual Study Start Date : 2025-08-01
Estimated Primary Completion Date : 2026-08-01
Estimated Study Completion Date : 2026-08-01

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years to 99 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria: Patients admitted to the ICU from January 2014 to December 2024 and had at least one positive blood culture for candidemia -Exclusion Criteria: Missing data
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  • Candidemia in Critically Ill Patients

    Location Details

    NCT06929494


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    Locations


    Not yet recruiting

    Israel,

    Meir Medical Center

    Beyon Kfar Saba, Israel,

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