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NCT06848530 | NOT YET RECRUITING | Movement Disorders


Neurophysiology of the Basal Ganglia, Thalamus, and Cerebellum in Patients With Movement Disorders
Sponsor:

University of Pennsylvania

Information provided by (Responsible Party):

Lauren Hammer

Brief Summary:

The research study is being conducted to better understand parts of the human brain called the cortex, basal ganglia, thalamus, and cerebellum in patients with movement disorders (such as Parkinson's disease, essential tremor, dystonia, or ataxia). These brain structures are involved in movement disorders. This study attempts to better understand the brain electrical activity associated with these disorders, both in patients with and without deep brain stimulation (DBS). Recordings are made from the scalp with a noninvasive electrode and/or through the DBS stimulator if the participant has a stimulator model that is able to sense brain activity. These recordings are analyzed along with measures of movement disorder symptoms to identify brain signal signatures of symptoms.

Condition or disease

Movement Disorders

Intervention/treatment

Prescribed Medications

Deep brain stimulation adjustment

Phase

NA

Study Type : INTERVENTIONAL
Estimated Enrollment : 100 participants
Masking : SINGLE
Primary Purpose : BASIC_SCIENCE
Official Title : Neurophysiology of the Basal Ganglia, Thalamus, and Cerebellum in Patients With Movement Disorders
Actual Study Start Date : 2025-05
Estimated Primary Completion Date : 2030-04
Estimated Study Completion Date : 2030-04

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • * Patients 18 years of age and above
  • * Any patient who has been diagnosed by a movement disorders neurologist with one of the following movement disorders:
  • * Parkinson's disease
  • * Dystonia
  • * Tremor, including essential tremor
  • * Cerebellar ataxia
  • * Other hyperkinetic movement disorders, such as chorea and tics
Exclusion Criteria
  • - Patients with dementia

Neurophysiology of the Basal Ganglia, Thalamus, and Cerebellum in Patients With Movement Disorders

Location Details

NCT06848530


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Locations


Not yet recruiting

United States, Pennsylvania

Pennsylvania Hospital

Philadelphia, Pennsylvania, United States, 19107

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