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NCT06844643 | RECRUITING | Axial Spondyloarthritis


The Disease Progression of Chinese Axial Spondyloarthritis in a Real-word Cohort Study
Sponsor:

China-Japan Friendship Hospital

Information provided by (Responsible Party):

Wei Ping Kong

Brief Summary:

An observational, ambispective cohort to learn about the disease progression of axial spondyloarthritis (axSpA) according to the changes from baseline in measures of disease activity, function, and imaging.

Condition or disease

Axial Spondyloarthritis

Ankylosing Spondylitis (AS)

Detailed Description:

This is an observational cohort study of Chinese patients (≥18 years of age) diagnosed with axSpA. Patients are followed at 4-6 month intervals. Data will be collected at baseline and at every follow-up time points. Primary outcomes are the structural damage measured with imaging(Conventional radiography, low-dose CT and MRI) and the disease activity measured with the Ankylosing Spondylitis Disease Activity Scale (ASDAS) and the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI). Secondary outcomes are inflammatory markers, Bath ankylosing spondylitis functional index (BASFI) and Bath ankylosing spondylitis metrology index (BASMI).

Study Type : OBSERVATIONAL
Estimated Enrollment : 2250 participants
Official Title : The Disease Progression of Chinese Axial Spondyloarthritis in a Real-word Cohort Study
Actual Study Start Date : 2025-03-01
Estimated Primary Completion Date : 2030-12-01
Estimated Study Completion Date : 2030-12-01

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • * Patients aged 18 years or older and diagnosed with the Assessment of Spondyloarthritis International Society axial spondyloarthritis criteria.
Exclusion Criteria
  • * Patients with serious disease in cardiovascular, kidney and blood and endocrine system; history of schizophrenia or epilepsy; pregnant or in lactation period.

The Disease Progression of Chinese Axial Spondyloarthritis in a Real-word Cohort Study

Location Details

NCT06844643


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Locations


RECRUITING

China,

China-Japan Friendship Hospital

Beijing, China,

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