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NCT06840587 | RECRUITING | Alzheimer Disease


Connect-Home: Alzheimer's Disease and Related Dementias
Sponsor:

University of North Carolina, Chapel Hill

Brief Summary:

This study is a parallel arm, cluster randomized trial (CRT) to test the efficacy of Connect-Home ADRD, a transitional care intervention focusing on Skilled Nursing Facility (SNF) patients with Alzheimer's disease and dementias and their caregivers during transitions from SNFs to home, assisted, living, and long-term care. The primary hypothesis is that the intervention will reduce caregiver strain (Aim 1) and patient neuropsychiatric symptoms (Aim 2).

Condition or disease

Alzheimer Disease

Dementia

Intervention/treatment

Connect-Home ADRD

Phase

NA

Detailed Description:

Connect-Home ADRD is a Donabedian-guided intervention that introduces new structure and processes to support Skilled Nursing Facility (SNF) staff delivery of transitional care for transitions to home, assisted living, or long-term care, and post-discharge transitional care by the Dementia Caregiving Specialist (DCS). The research objective is to test the efficacy of Connect-Home ADRD, a transitional care intervention, targeting Skilled Nursing Facility (SNF) patients with Alzheimer's disease and related dementias (ADRD) and their primary caregivers who discharge home and other settings of care. The study will be set in 12 North Carolina SNFs and in the patient's discharge destination (during intervention periods only). Using a cluster-randomized trial design, twelve SNFs will be randomly allocated to an intervention group (N=6 SNFs) and to a control group (N=6 SNFs) by a study statistician masked to SNF identity. 360 dyads of SNF patients with ADRD and caregivers will be enrolled in 12 SNFs.

Study Type : INTERVENTIONAL
Estimated Enrollment : 360 participants
Masking : SINGLE
Masking Description : Before enrollment of SNF patients and caregivers, randomization of the 12 SNFs will be conducted by blinded study staff who will use codes to conceal allocation and randomly assign SNFs in a 1:1 ratio to intervention and control arms. Study staff masked to study arm will assess outcomes, in a telephone-based interview with caregivers in both arms, 30 days after SNF discharge, this is for research purposes only. Research coordinators (RCs) will conduct 30-day electronic health record (EHR) reviews after dyads complete study participation, as EHR content has the potential to reveal study arm assignment. As with most behavioral clinical interventions, participants and care providers cannot be masked.
Primary Purpose : SUPPORTIVE_CARE
Official Title : Transitional Care for Skilled Nursing Facility Patients With Alzheimer's Disease and Related Dementias and Their Caregivers: a Cluster Randomized Trial
Actual Study Start Date : 2025-04-04
Estimated Primary Completion Date : 2027-06-30
Estimated Study Completion Date : 2027-06-30

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 19 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • Patients
    • * Ability to speak English
    • * Goal of discharge to home, assisted living, or long-term care
    • * Diagnosis of dementia
    • * Having a caregiver willing to participate
    • Caregivers
      • * Ability to speak English
      • * Legally authorized representative (LAR) who also provides support for the person with ADRD
      • Inclusion criteria for SNFs
        • * Location within 120 miles of UNC-Chapel Hill
        • * Admission of at least 75 SNF patients per year
        Exclusion Criteria
        • Patients
          • * Planned hospital readmission for procedures or treatments within 30 days post enrollment.
          • Caregivers
            • * LAR is a court-appointed guardian.

Connect-Home: Alzheimer's Disease and Related Dementias

Location Details

NCT06840587


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Locations


RECRUITING

United States, North Carolina

University of North Carolina at Chapel Hill

Chapel Hill, North Carolina, United States, 27599

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