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NCT06839274 | NOT YET RECRUITING | OVARIAN STIMULATION


Follicular Volume At the Time of Final Oocyte Maturation in Poor Responders, and Its Correlation with Oocyte Maturity
Sponsor:

ART Fertility Clinics LLC

Brief Summary:

Women with a severely diminished ovarian reserve and monofollicular growth are at a higher risk of premature ovulation as well as poor quality oocytes. Our group showed previously that women with severely diminished ovarian reserve benefit from receiving the final oocyte maturation at smaller follicle sizes in terms of reducing the risk of premature ovulation and finding mature oocytes even out of small size follicles. Adding the measurement of the follicular volume at the time of final oocyte maturation might provide more information on the proper timing of trigger administration compared to the follicular size alone, hormonal profile as well as previous stimulation attempts. Setting a cutoff value of follicular volume for trigger might help to avoid premature ovulation and possibly increase the chances of ending up with a euploid embryo.

Condition or disease

OVARIAN STIMULATION

Intervention/treatment

transvaginal Ultrasound

Study Type : OBSERVATIONAL
Estimated Enrollment : 100 participants
Official Title : Follicular Volume At the Time of Final Oocyte Maturation in Poor Responders, and Its Correlation with Oocyte Maturity
Actual Study Start Date : 2025-04-30
Estimated Primary Completion Date : 2025-11-30
Estimated Study Completion Date : 2025-12-31

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years to 48 Years
Sexes Eligible for Study: FEMALE
Accepts Healthy Volunteers: 1
Criteria
Inclusion Criteria
  • * Reproductive age group: 18 -48
  • * undergoing ovarian stimulation for oocyte vetrification
  • * undergoing IVF/ ICSI with PGT-A / PGT-M / PGT- Sr
  • * less than or equal to 3 AFC on initiation of stimulation
  • * follicular phase stimulation
Exclusion Criteria
  • * surgically retrieved sperm

Follicular Volume At the Time of Final Oocyte Maturation in Poor Responders, and Its Correlation with Oocyte Maturity

Location Details

NCT06839274


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Locations


Not yet recruiting

United Arab Emirates,

ART Fertility Clinics

Abu Dhabi, United Arab Emirates, 60202

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