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NCT06815666 | NOT YET RECRUITING | Soft Tissue Sarcoma (STS)

BAL Fluid Biomarkers in Sarcoma
Sponsor:

University Health Network, Toronto

Brief Summary:

This is a single-centre, Phase II, prospective study designed to assess BALF and TA-derived biomarkers in relation to metastatic burden in STS patients. BALF and TA samples will be collected during routine bronchoscopy performed as part of standard care at Toronto General Hospital (TGH). Additionally, tissue samples of lung metastases and adjacent normal lung will be collected and used to correlate the identified biomarkers.

Condition or disease

Soft Tissue Sarcoma (STS)

Bronchoalveolar Lavage (BAL)

Bronchoalveolar Lavage Fluid

Intervention/treatment

Bronchoscopy & Metastasectomy

Phase

PHASE2

Study Type : INTERVENTIONAL
Estimated Enrollment : 70 participants
Masking : NONE
Primary Purpose : TREATMENT
Official Title : Prospective Study of Biomarkers Derived From Bronchoalveolar Lavage Fluid to Predict Outcomes in Soft-Tissue Sarcomas
Actual Study Start Date : 2025-04-01
Estimated Primary Completion Date : 2032-04-01
Estimated Study Completion Date : 2032-04-01

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • 1. Age ≥ 18 years
  • 2. Ability to understand and willingness to sign a written informed consent document
  • 3. Diagnosed with soft tissue sarcoma
  • 4. Undergoing resection of lung lesion as part of standard care
Exclusion Criteria
  • 1. History of another invasive malignancy, except for non-melanoma skin cancer or tumors curatively treated with no evidence of disease for ≥ 2 years
BAL Fluid Biomarkers in Sarcoma

Location Details

NCT06815666

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How to Participate

Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.

Locations

Not yet recruiting

Canada, Ontario

Radiation Medicine Program, Princess Margaret Cancer Centre, University Health Network

Toronto, Ontario, Canada, M5G 2M9