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NCT06776965 | RECRUITING | Rheumatoid Arthritis


Ultra Processed Foods Consumption and Impact in Rheumatic Diseases.
Sponsor:

Lyon Civilian Hospices

Brief Summary:

Ultra-processed foods (UPF) represent one of the mainstays of today's diet. They are defined by the NOVA classification system. It was demonstrated that UPF consumption was associated with activity of inflammatory bowel diseases with underlying mechanisms not fully identified yet. It is suspected that UPF constituents could modify the gut microbiota, increase intestinal barrier permeability and directly engage immune surveillance systems, effects that could individually or synergistically increase the risk of immunomediated diseases. As some pathophysiological mechanisms are shared among IBD and rheumatic diseases, we have wondered if UPF consumption could be associated with increased risk of rheumatic disease and/or with their activity. Our primary aim will be to study the pattern of UPF consumption in patients with rheumatic diseases. Our secondary objectives will be to study the activity of diseases according to UPF consumption.

Condition or disease

Rheumatoid Arthritis

Spondylowarthritis

Osteoarthritis

Intervention/treatment

Dietary Questionnaire

Evaluation of disease activity (DAS-28, ASDAS, EVA, number of swollen joints, number of painful joint, nocturnal pain, morning stiffness)

Study Type : OBSERVATIONAL
Estimated Enrollment : 240 participants
Official Title : Impact of Ultra-processed Foods in a Population of Patients With Chronic Rheumatic Diseases (Rheumatoid Arthritis, Spondyloarthritis, Osteoarthritis).
Actual Study Start Date : 2025-03-31
Estimated Primary Completion Date : 2026-03-31
Estimated Study Completion Date : 2026-11-30

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • * Age \> 18 years
  • * chronic rheumatic disease (Rheumatoid arthritis, spondyloarthritis, osteoarthritis)
  • * ability to perform questionnaires
Exclusion Criteria
  • * Judicial protection measure
  • * Refusal to participate in the study
  • * Suffering from 2 rheumatic disease simultaneously

Ultra Processed Foods Consumption and Impact in Rheumatic Diseases.

Location Details

NCT06776965


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Locations


RECRUITING

France,

Edouard Herriot Hospital

Lyon, France, 69003

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