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NCT06700122 | RECRUITING | Vitamin D Deficiency

Clinical Comparative Evaluation of the Use of Photodynamic Therapy in Conjunction With the Use of Vitamin D in Management Stage II Grade B Periodontitis Patients
Sponsor:

Cairo University

Information provided by (Responsible Party):

Marwa Halll

Brief Summary:

Clinical Comparative Evaluation of the use of Photodynamic Therapy in conjunction with the use of Vitamin D in management Stage II Grade B Periodontitis Patients: A Randomized controlled clinical trial.

Condition or disease

Vitamin D Deficiency

Intervention/treatment

non-surgical periodontal therapy (SRP) and Photodynamic therapy (PDT) with systemic vitamin D

Phase

NA

Detailed Description:

This randomized clinical trial evaluates the effect of Photodynamic therapy alone with SRP versus Photodynamic therapy with SRP and Vitamin D regarding Clinical evaluation 1. Clinical attachment loss (CAL) 2. Probing pocket depth (PPD) 3. Bleeding on probing (BOP)

Study Type : INTERVENTIONAL
Estimated Enrollment : 24 participants
Masking : DOUBLE
Primary Purpose : TREATMENT
Official Title : Clinical Comparative Evaluation of the Use of Photodynamic Therapy in Conjunction With the Use of Vitamin D in Management Stage II Grade B Periodontitis Patients: A Randomized Controlled Clinical Trial.
Actual Study Start Date : 2025-06-01
Estimated Primary Completion Date : 2025-06-15
Estimated Study Completion Date : 2025-06-15

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years to 50 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: 1
Criteria
Inclusion Criteria
  • * Systemic healthy patients
  • * Patients aged \> 25 years
  • * Patients suffering from stage II periodontitis with grade B were included in this study, according to 2017 world workshop classification of periodontal disease.
  • * Patients with interdental clinical attachment loss (CAL) of 3-4 mm with radiographic evidence of bone loss extending to coronal third of the root.
  • * Radiographic bone loss (RBL) will be diagnosed using periapical parallel technique using 6 radiographic images for full mouth (3- radiographic images for maxillary arch and 3- radiographic images for mandibular arch) including anterior, canine region and posterior teeth at baseline for diagnosis.
  • * No history of previous periodontal therapy.
  • * No taken medications known to interfere healing or periodontal tissue health such as anticonvulsants, calcium channel blockers, or immunosuppressant drugs.
  • * No previous periodontal surgery at involved sites.
  • * Good oral hygiene and good compliance with the plaque control instructions following initial therapy.
  • * Neither taken antibiotics within the last three months nor nonsteroidal anti-inflammatory drugs within the last three months
  • * Absence of diseases or conditions that would interfere with wound healing such as diabetes mellitus or coagulation disorders
Exclusion Criteria
  • Patients taking Vitamin D as a nutritional supplement were excluded from the study
  • * Smoking habits
  • * Pregnant and lactating mothers
  • * Patients who have been received periodontal surgery in the study area during the last 6 months.
Clinical Comparative Evaluation of the Use of Photodynamic Therapy in Conjunction With the Use of Vitamin D in Management Stage II Grade B Periodontitis Patients

Location Details

NCT06700122

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Locations

RECRUITING

Egypt,

Marwa Halll

Cairo, Egypt, 02