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NCT06692257 | NOT YET RECRUITING | Molar Hypomineralization, Incisor

Orofacial Functions in Individuals With and Without Molar Incisor Hypomineralization
Sponsor:

University of Nove de Julho

Information provided by (Responsible Party):

Sandra Kalil Bussadori

Brief Summary:

Molar incisor hypomineralization (MIH) is a qualitative developmental defect of the enamel with a complex, multifactorial nature and a significant genetic component that predominantly affects the permanent first molars and, occasionally, the permanent incisors. Individuals with MIH have a compromised stomatognathic system manifested by muscle hyperactivity under postural and dynamic conditions. However, there is a gap in knowledge on the specific functional abnormalities that these individuals experience. Early identification and intervention, with a focus on the prevention of orofacial dysfunctions and deviations in facial growth and development, are aspects of the utmost importance. Therefore, the aim of the proposed study is to perform a comparative analysis of orofacial functions with an emphasis on breathing and chewing patterns in individuals with and without MIH. Methods and Analysis: Assessments will be performed using the Nordic Orofacial Test - Screening (NOT-S). Descriptive statistics will be performed and comparisons will be made using the chi-square test, adopting a 5% significance level.

Condition or disease

Molar Hypomineralization, Incisor

Intervention/treatment

Observation

Study Type : OBSERVATIONAL
Estimated Enrollment : 56 participants
Official Title : Orofacial Functions With Emphasis on Breathing and Chewing Patterns in Individuals With and Without Molar Incisor Hypomineralization: Observational Study Protocol
Actual Study Start Date : 2025-03-01
Estimated Primary Completion Date : 2025-07-01
Estimated Study Completion Date : 2025-11-01

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 6 Years to 12 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: 1
Criteria
Inclusion Criteria
  • * Children 6 to 12 years of age with a complete mixed dentition with all first molars present and in occlusion;
  • * Having all first molars erupted, without caries or previous treatment;
  • * Inclusion criteria for the MIH group: at least one permanent molar with indices compatible with MIH (code 2, 21, 22 and 3 - Ghanim criteria).
Exclusion Criteria
  • * Children with amelogenesis and dentinogenesis imperfecta;
  • * Children undergoing orthodontic treatment;
  • * Children with a genetic syndrome;
  • * Children with the premature loss of deciduous teeth;
  • * Children with acute respiratory problems;
  • * Children in treatment.
Orofacial Functions in Individuals With and Without Molar Incisor Hypomineralization

Location Details

NCT06692257

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