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NCT06689020 | NOT YET RECRUITING | Recruitment

Positive Expiratory Pressure (PEP) and Continuous High-frequency Oscillation (CHFO) on Lung RECRUITment Using Electrical Impedance Tomography (EIT) - The PEP-RECRUIT Study
Sponsor:

University of Genova

Information provided by (Responsible Party):

Lorenzo Ball

Brief Summary:

This single-center observational study aims to assess the effects of continuous high-frequency oscillation (CHFO) and continuous positive expiratory pressure (CPEP) therapy on lung recruitment using electrical impedance tomography (EIT) in spontaneously breathing patients admitted to the intensive care unit.

Condition or disease

Recruitment

Respiratory Failure

Intervention/treatment

Continuous high-frequency oscillation (CHFO) and continuous positive expiratory pressure (CPEP) therapy

Study Type : OBSERVATIONAL
Estimated Enrollment : 26 participants
Official Title : Effect of Continuous High-frequency Oscillation (CHFO) and Continuous Positive Expiratory Pressure (CPEP) Therapy on Lung RECRUITment Using Electrical Impedance Tomography (EIT) - The PEP-RECRUIT Study
Actual Study Start Date : 2024-12-01
Estimated Primary Completion Date : 2025-06-01
Estimated Study Completion Date : 2025-07-01

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • * Patients who require pulmonary expansion and airway clearing as per clinical indication
  • * Patients who provide valid informed consent according to local regulations
  • * PaO2/FiO2 \< 200 mmHg at inclusion
  • * Patient on the Airway Care Score (ACS) \< 7
Exclusion Criteria
  • * Refuse to participate
  • * Age \< 18 years
  • * Hemodynamic instability, defined as systolic arterial pressure \< 90 mmHg or mean pressure \< 60 mmHg
  • * Contraindication to using an EIT (i.e., pacemaker or defibrillator)
  • * Inability to properly position the EIT device for anatomical reasons
Positive Expiratory Pressure (PEP) and Continuous High-frequency Oscillation (CHFO) on Lung RECRUITment Using Electrical Impedance Tomography (EIT) - The PEP-RECRUIT Study

Location Details

NCT06689020

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How to Participate

Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.

Locations

Not yet recruiting

Italy, GE

Anesthesiology and Intensive Care Clinic Unit, IRCCS San Martino Polyclinic Hospital

Genova, GE, Italy, 16132