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NCT06688994 | NOT YET RECRUITING | Acute Kidney Injuries


VITAMIN D METABOLITES AS BIOMARKERS FOR THE IDENTIFICATION OF KIDNEY INJURY IN CARDIAC SURGERY
Sponsor:

University Health Network, Toronto

Brief Summary:

We will be measuring vitamin D metabolites in blood samples drawn from patients undergoing cardiac surgery to determine the correlation with renal function as assessed by serum creatinine. We will include 20 patients in each of the following 3 groups based on serum creatinine measured within 28-days of surgery: 1) normal kidney function (eGFR \> 60 mL/min, n=20), 2) moderate impaired kidney function, eGFR between 30 and 60 mL/min (n=20) and 3) severe kidney dysfunction eGFR \< 30 mL/min (n=20).

Condition or disease

Acute Kidney Injuries

Chronic Renal Diseases

Study Type : OBSERVATIONAL
Estimated Enrollment : 60 participants
Official Title : Vitamin D Metabolites as Biomarkers for the Identification of Kidney Injury in Cardiac Surgery
Actual Study Start Date : 2024-11-20
Estimated Primary Completion Date : 2025-07-31
Estimated Study Completion Date : 2025-12-31

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • * ≥ 18 years
  • * Patients undergoing cardiac surgery
  • * Serum Creatinine measured with 28 days of surgery
  • Exclusion Criteria
  • * Exogeneous calcitriol (1,25(OH)2D3) intake
  • * History of parathyroidectomy
  • * Patients with liver or kidney cancer
  • * Patients with liver disease (e.g. liver failure, cirrhosis)

  • VITAMIN D METABOLITES AS BIOMARKERS FOR THE IDENTIFICATION OF KIDNEY INJURY IN CARDIAC SURGERY

    Location Details

    NCT06688994


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    Locations


    Not yet recruiting

    Canada, Ontario

    University Health Network-Toronto General Hospital

    Toronto, Ontario, Canada, M5G 2C4

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