Thinking of joining a study?

Register your interest

NCT06674772 | RECRUITING | Headache (Migraine)


Molecular Phenotyping of Migraine Patients According to Sex and Age Through CGRP Quantification
Sponsor:

Vall d'Hebron Research Institute University Hospital

Brief Summary:

Patients will be asked to visit the study center 2 times, the first time for clinical assessment and a second time for sample collection. Healthy controls will only be asked to visit the study center for sample collection. A sample of blood and saliva will be collected in order to measure CGRP levels and DNA and hormone testing.

Condition or disease

Headache (Migraine)

Migraine

Migraine Headache

Migraine with Aura

Migraine Without Aura

Episodic Migraine

Chronic Migraine Headache

Chronic Migraine, Headache

Episodic Migraine Headache

Intervention/treatment

Saliva test

Detailed Description:

CGRP is a neuropeptide related to migraine pathophysiology, which can be found in human saliva in both patients and healthy controls. The differences in CGRP levels may help us explain the differences in the treatment response. A sample of saliva will be collected in order to measure CGRP levels and a blood sample will be collected in order to conduct a DNA test and hormones test.

Study Type : OBSERVATIONAL
Estimated Enrollment : 440 participants
Official Title : Molecular phenotype of patients with migraine according to age and sex through the quantification of CGRP in saliva to perform precision medicine: FAST study
Actual Study Start Date : 2022-11-29
Estimated Primary Completion Date : 2025-04-30
Estimated Study Completion Date : 2025-05

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 6 Years to 75 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: 1
Criteria
Inclusion Criteria
  • * Migraine patients according to ICHD-3 criteria
  • * Healthy controls paired to patient age and sex, without headache and without first degree family history of headache.
Exclusion Criteria
  • * Presence of any major medical or neurological illness.
  • * Presence of any salivary gland malfunction.
  • * Abuse or dependence to tobacco, alcohol or any drug in the previous 12 months before the enrollment.
  • * Active migraine preventive treatment.
  • * Pregnant or breastfeeding female.

Molecular Phenotyping of Migraine Patients According to Sex and Age Through CGRP Quantification

Location Details

NCT06674772


Please Choose a site



How to Participate

Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.

Locations


RECRUITING

Spain,

Vall d'Hebron University Hospital

Barcelona, Spain, 08035

Loading...