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NCT06653374 | COMPLETED | Preterm Birth

Perinatal Conditions Influencing Morbidity, Mortality, and Medical Care in Newborns
Sponsor:

ISIDRO AYORA OBSTETRIC GYNECO HOSPITAL

Information provided by (Responsible Party):

Santiago Vasco-Morales

Brief Summary:

This study focuses on understanding the conditions that affect newborn health and survival from pregnancy to the first weeks of life at the Isidro Ayora Hospital. The investigators will review data from 2008 to 2022 to identify key factors that may contribute to complications, help improve medical care, and reduce risks for newborns. By doing so, we aim to provide better support to families, healthcare providers, and ensure safer births.

Condition or disease

Preterm Birth

Low Birth Weight

Intrauterine Growth Restriction (IUGR)

Perinatal Asphyxia

Neonatal Sepsis

Respiratory Distress Syndrome (RDS)

Neonatal Jaundice

Congenital Malformations

Neonatal Hypoglycemia

Gestational Diabetes Mellitus (GDM)

Placental Abruption

Preterm Premature Rupture of Membranes (PPROM)

Hypertension, Pregnancy-Induced

Pre-Eclampsia

Intervention/treatment

Infant, Premature

Detailed Description:

This research investigates the impact of various perinatal conditions-such as maternal health, prenatal complications, delivery methods, and neonatal management-on morbidity and mortality rates in newborns treated at the Isidro Ayora Obstetric-Gynecologic Hospital. Using a retrospective cohort design, the study analyzes data from 2008 to 2022 to identify patterns and correlations between perinatal factors and neonatal outcomes, aiming to inform evidence-based clinical practices and enhance neonatal care protocols. Key aspects include evaluating the influence of gestational age, birth weight, maternal comorbidities (e.g., hypertension, diabetes), and obstetric complications on the health of neonates. Outcomes of interest include NICU admissions, length of hospital stay, and incidence of conditions such as respiratory distress syndrome, sepsis, and neonatal mortality. Findings will contribute to improving resource allocation, optimizing care strategies, and potentially guiding policy decisions to reduce adverse neonatal outcomes.

Study Type : OBSERVATIONAL
Estimated Enrollment : 26000 participants
Official Title : "Perinatal Conditions That Influence Morbidity, Mortality and Medical Care in Neonates at the Isidro Ayora Gineco Obstetric Hospital, January 2008-December 2022"
Actual Study Start Date : 2023-11-12
Estimated Primary Completion Date : 2024-09-10
Estimated Study Completion Date : 2024-09-10

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: to 28 Days
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • * Neonates born at the Isidro Ayora Obstetric-Gynecologic Hospital between January 2008 and December 2022.
  • * Live-born neonates with complete medical records in the hospital's perinatal database.
  • * Neonates whose mothers received antenatal care and delivered at the hospital. Availability of maternal and neonatal data, including gestational age, birth weight, and outcome information.
Exclusion Criteria
  • * Neonates with incomplete or missing medical records.
  • * Neonates born outside the hospital and referred postnatally.
  • * Stillbirths and pregnancies terminated due to maternal or fetal indications.
  • * Neonates discharged to other facilities immediately after birth without follow-up data in the hospital\'s database.
Perinatal Conditions Influencing Morbidity, Mortality, and Medical Care in Newborns

Location Details

NCT06653374

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How to Participate

Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.

Locations

Not yet recruiting

Ecuador, Pichincha

Isidro Ayora Obstetric Gynecological Hospital

Quito, Pichincha, Ecuador, 170601