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NCT06630845 | RECRUITING | Metastatic Cancer

Comparison of Whole Body DWI to FDG PET
Sponsor:

University of California, San Francisco

Brief Summary:

This is a single arm prospective trial that evaluates whole body diffusion weight imaging (DWI) compared to 18F-fludeoxyglucose (FDG) Positron Emission Tomography with Magnetic resonance imaging (PET/MRI) in participants with known metastatic cancer.

Condition or disease

Metastatic Cancer

Intervention/treatment

Fluorodeoxyglucose F18

Positron Emission Tomography combined with Magnetic resonance imaging (PET/MRI)

Whole Body Magnetic Resonance Imaging with Diffusion-Weighted Imaging (WB-MRI-DWI)

General Electric (GE) SIGNA PET/MR

Phase

NA

Detailed Description:

PRIMARY OBJECTIVE: I. Correlation of DWI and FDG to detect disease. SECONDARY OBJECTIVE: I. Inter-reader variability of DWI interpretation by region. OUTLINE: Participants will be imaged at a single timepoint using whole body DWI concurrent with FDG PET/MRI within 60 days of receiving a non-FDG PET (either PET/CT or PET/MRI). There will be an optional PET/MRI performed within six months of the original study. Participants will be followed up through a medical records review for up to two years.

Study Type : INTERVENTIONAL
Estimated Enrollment : 30 participants
Masking : NONE
Primary Purpose : DIAGNOSTIC
Official Title : Comparison of Whole Body DWI to FDG PET Using PET/MRI
Actual Study Start Date : 2025-02-06
Estimated Primary Completion Date : 2027-10-31
Estimated Study Completion Date : 2029-10-31

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • 1. Age ≥ 18 years.
  • 2. Non FDG PET imaging study scheduled to be performed within 60 days (before or after) of the research PET/MRI.
  • 3. Ability to understand a written informed consent document, and the willingness to sign it.
  • 4. Diagnosis of metastatic cancer.
Exclusion Criteria
  • 1. Unlikely to comply with protocol procedures, restrictions and requirements and judged by the Investigator to be unsuitable for participation.
  • 2. Individuals with contraindications to MRI. This will be determined through review of the UCSF MRI screening form by qualified site personnel
Comparison of Whole Body DWI to FDG PET

Location Details

NCT06630845

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How to Participate

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Locations

RECRUITING

United States, California

University of California, San Francisco

San Francisco, California, United States, 94143