Cairo University
Hadeer Nasser Hammad Aboeldahb
The goal of this clinical trial is to Clinical and Radiographic Evaluation of Hyaluronic Acid (Gengigel Teething) Versus Mineral Trioxide Aggregate( Angelus) as Pulpotomy Agent in Vital Primary Molars. The main question it aims to answer is: Is there a difference in the clinical or radiographic success when using Hyaluronic acid (Gengigel Teething, Ricerfarma , Italy) versus mineral trioxide aggregate (Angelus, Londrina ,Brazil) in pulpotomy of carious primary molars in children?
Pulpotomies Primary Teeth
Pulp Disease, Dental
Hyaluronic acid pulpotomy
mineral trioxide aggregate pulpotomy
PHASE1
Preservation of primary dentition decreases the risk of developing any occlusal abnormalities caused by premature loss of primary teeth, which are considered natural space maintainers for the successor permanent teeth, therefore vital pulp therapy is of a big concern in the research field in pediatric dentistry. One of the most commonly used regenerative materials in pulpotomies is Mineral Trioxide Aggregate (MTA) which showed a high success rate clinically and radiographically when compared to other materials due to its biocompatibility, antibacterial properties and excellent sealing ability . However it has some drawbacks such as difficult manipulation and handling because it is supplied in powder and liquid form which need mixing. Mixing is operator dependent and may be not uniform if handled wrongly, technique sensitive, potential discoloration, and long setting time. Hyaluronic acid have been introduced as a new biologically based therapeutics directed at preserving pulp vitality. Owing to good handling characteristics, biocompatibility, odontogenic property. non-toxic, biodegradable ,non-immunogenic , anti-inflammatory and antibacterial action, hyaluronic acid is a promising pulpotomy agent Furthermore, the use of a gel containing HA facilitated faster healing in laser-induced wounds by secondary intention. HA tends to be helpful in the treatment of swelling and trismus as well as the inflammatory reaction after third molar extraction. The benefits of this study to the participants: A cheaper , faster and easier clinical procedure leads to a more efficient dental treatment, which could develop positive attitude of children towards dentistry. The benefits of this study to the population: 1. Providing better quality of dental treatment. 2. Enhance the overall oral health of children. The benefits of this study to the clinicians: 1. Providing a new biological and alternative treatment option. 2. Decreased chairside time owing to its better manipulation and less technique sensitive . 3. cheaper and accessible alternative .
| Study Type : | INTERVENTIONAL |
| Estimated Enrollment : | 34 participants |
| Masking : | TRIPLE |
| Primary Purpose : | TREATMENT |
| Official Title : | Clinical and Radiographic Evaluation of Hyaluronic Acid (Gengigel Teething) Versus Mineral Trioxide Aggregate( Angelus) as Pulpotomy Agent in Vital Primary Molars: A Randomized Clinical Trial |
| Actual Study Start Date : | 2025-03 |
| Estimated Primary Completion Date : | 2026-03 |
| Estimated Study Completion Date : | 2026-04 |
Information not available for Arms and Intervention/treatment
| Ages Eligible for Study: | 4 Years to 8 Years |
| Sexes Eligible for Study: | ALL |
| Accepts Healthy Volunteers: |
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Cairo University
Cairo, Egypt,