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NCT06606366 | NOT YET RECRUITING | Neoplasm Malignant

Study on the Contribution of the Genetic Tumor Profile Obtained by Circulating Tumor DNA Analysis in the Multidisciplinary Molecular Biology Meeting of Eastern PACA
Sponsor:

Antoine Lacassagne Center

Brief Summary:

This study will evaluate the diagnostic performance of liquid biopsy for identifying molecular abnormalities among patients managed by the Multidisciplinary Molecular Biology Meeting. The gold standard considered in this study is the solid biopsy.

Condition or disease

Neoplasm Malignant

Intervention/treatment

Blood sample taken for the liquid biopsy

Phase

NA

Study Type : INTERVENTIONAL
Estimated Enrollment : 216 participants
Masking : NONE
Primary Purpose : DIAGNOSTIC
Official Title : Study on the Contribution of the Genetic Tumor Profile Obtained by Circulating Tumor DNA Analysis in the Multidisciplinary Molecular Biology Meeting of Eastern PACA
Actual Study Start Date : 2025-02
Estimated Primary Completion Date : 2027-05
Estimated Study Completion Date : 2027-05

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • * Over 18 years old.
  • * Advanced-stage malignant solid tumor managed in a non-curative context.
  • * Patient eligible for Multidisciplinary molecular biology meeting with available archived tumor material (frozen or FFPE block, less than 5 years old) or a biopsiable tumor lesion.
  • * Performance status of 0 or 1.
  • * Patient able to read, write, and understand the French language.
  • * Patient has read the information sheet and signed the informed consent.
  • * Patient has social security coverage.
Exclusion Criteria
  • * Previous or concurrent cancer diagnosed or treated within the last 5 years, except for in situ carcinoma of the cervix, basal cell or squamous cell carcinoma of the skin, and adequately treated in situ carcinoma of the bladder.
  • * Severe or uncontrolled systemic disease.
  • * Any condition which, in the investigator's judgment (geographical, social, or psychological factors, etc.), makes the patient unable to comply with study follow-up and procedures.
  • * Patient considered a vulnerable person; vulnerable persons are defined in Articles L1121-5 to L1121-8
    • * Pregnant women, women in labor, and breastfeeding mothers,
    • * Persons deprived of liberty by judicial or administrative decision, individuals hospitalized without consent under Articles L. 3212-1 and L. 3213-1 who do not fall under the provisions of Article L. 1121-8,
    • * Persons admitted to a healthcare or social institution for reasons other than research,
    • * Adults unable to give their consent.
Study on the Contribution of the Genetic Tumor Profile Obtained by Circulating Tumor DNA Analysis in the Multidisciplinary Molecular Biology Meeting of Eastern PACA

Location Details

NCT06606366

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How to Participate

Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.

Locations

Not yet recruiting

France, Provence-Alpes-Côte d’Azur

Antoine Lacassagne Center

Nice, Provence-Alpes-Côte d’Azur, France, 06189