Thinking of joining a study?

Register your interest

NCT06593379 | RECRUITING | Suicide


Mobile Intervention for Suicidal Thoughts
Sponsor:

VA Office of Research and Development

Brief Summary:

One of the factors that contributes to suicide risk is what is known as a "suicidal belief system." This belief system is made up of several cognitions that been associated with suicide risk among military personnel. Modification of these cognitions may reduce suicidal thoughts and behaviors. The study team has developed a brief mobile intervention entitled the Mobile Intervention for Suicidal Thoughts (MIST) that uses evidence-based interpretation bias modification techniques to reduce these suicide cognitions. The goal of this project is to is to conduct a pilot trial of the MIST intervention to evaluate whether it is feasible an acceptable as an adjunct treatment for Veterans with suicidal ideation.

Condition or disease

Suicide

Intervention/treatment

Safety planning

Treatment as usual

MIST Intervention

Phase

NA

Detailed Description:

One of the factors that contributes to suicide risk is what is known as a "suicidal belief system." This belief system is made up of several cognitions, including hopelessness, thwarted belongingness, perceived burdensomeness, unlovability, unbearability, and unsolvability. These cognitions have all been associated with suicide risk among military personnel. Modification of these cognitions may reduce suicidal thoughts and behaviors. The study team has developed a brief mobile intervention entitled the Mobile Intervention for Suicidal Thoughts (MIST) that uses evidence-based interpretation bias modification techniques to reduce these suicide cognitions. The goal of this project is to is to conduct a pilot trial of the MIST intervention to evaluate whether it is feasible an acceptable as an adjunct treatment for Veterans with suicidal ideation. The investigators will conduct a pilot randomized controlled trial (RCT), in which 50 Veterans with suicidal ideation will be randomized to either MIST plus Treatment as Usual and Safety Planning versus Treatment as Usual and Safety Planning. The central hypothesis is that Veterans will find MIST acceptable and will be willing to use it to reduce their suicidal thoughts.

Study Type : INTERVENTIONAL
Estimated Enrollment : 50 participants
Masking : DOUBLE
Masking Description : The investigator and outcomes assessors will be blinded to the participant condition.
Primary Purpose : TREATMENT
Official Title : Pilot Randomized Controlled Trial of the Mobile Intervention for Suicidal Thoughts
Actual Study Start Date : 2025-09-03
Estimated Primary Completion Date : 2027-08-02
Estimated Study Completion Date : 2027-09-30

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • * Veterans using the Durham VA Health Care System
  • * Endorsing suicidal ideation without intent in the last 30 days, established via C-SSRS
  • * Meet at least every 4 months with a mental health provider, established via chart review chart
  • * Can read at least 6th grade level material, established by their demonstrated ability to read the consent form and answer basic questions about it
Exclusion Criteria
  • * Currently in a period of active psychosis or mania, established via the SCID-5
  • * Currently meeting criteria for a moderate or severe alcohol or substance use disorder, established via the SCID-5
  • * Endorsing suicidal intent, established via C-SSRS
  • * Exhibit current prominent suicidal or homicidal ideation requiring immediate intervention
  • * Have used the MIST intervention before as part of another research study

Mobile Intervention for Suicidal Thoughts

Location Details

NCT06593379


Please Choose a site



How to Participate

Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.

Locations


RECRUITING

United States, North Carolina

Durham VA Medical Center, Durham, NC

Durham, North Carolina, United States, 27705-3875

Loading...