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NCT06574282 | RECRUITING | Hypophosphatasia


Characteristics of Hypophosphatasia in Adult Patients in Rheumatology and Their Value in Developing an Algorithm to HPP-diagnosis - the COHIR Multi-center Study
Sponsor:

University of Bonn

Information provided by (Responsible Party):

Valentin Schäfer

Brief Summary:

Non-interventional, prospective, multi-center investigation with exploratory data analysis to assess the proportion of patients with hypophosphatasia presenting at departments of rheumatology and to establish an algorithm to HPP diagnosis

Condition or disease

Hypophosphatasia

Intervention/treatment

Second alkaline phosphatase measurement

Detailed Description:

Acronym: Expansion: HPP =Hypophosphatasia COHIR ="Characteristics of Hypophosphatasia in Adult Patients in Rheumatology" ALPL =Alkaline Phosphatase

Study Type : OBSERVATIONAL
Estimated Enrollment : 720 participants
Official Title : The COHIR Multi-center Study - a Non-interventional, Prospective, Multi-center Investigation With Exploratory Data Analysis to Assess the Proportion of Patients With Hypophosphatasia Presenting at the Department of Rheumatology and Establishment of an Algorithm to HPP Diagnosis.
Actual Study Start Date : 2024-08-25
Estimated Primary Completion Date : 2027-09
Estimated Study Completion Date : 2027-09

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • * Written informed consent
  • * Age \> 18 years
  • * Clinical suspicion of hypophosphatasia
  • * Evidence of an abnormal ALP (ALP below LLN) within the clinical routine screening
Exclusion Criteria
  • * Failure to meet the inclusion criteria listed above

Characteristics of Hypophosphatasia in Adult Patients in Rheumatology and Their Value in Developing an Algorithm to HPP-diagnosis - the COHIR Multi-center Study

Location Details

NCT06574282


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Locations


RECRUITING

Germany, North Rhine-Westphali

Clinic of Internal Medicine III, Department of Oncology, Haematology, Rheumatology and Clinical Immunology, University Hospital Bonn

Bonn, North Rhine-Westphali, Germany, 53127

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