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NCT06571747 | RECRUITING | Cardiovascular Diseases

Kaiser Permanente VACCination Improvement with Nudge-based CardiovAscular Targeted Engagement
Sponsor:

Kaiser Permanente

Brief Summary:

In randomized clinical trials and observational studies, influenza vaccination is effective in reducing influenza-related illness and hospitalizations and potentially cardiovascular (CV) events and mortality in select populations. However, the potential population-level benefit of influenza vaccination is limited by its uptake. Novel implementation strategies to improve vaccination uptake are needed. KP VACCINATE is a multicenter, sequential, individual-level randomized controlled implementation trial examining the effectiveness of a CV-focused nudging communication vs. usual care communication on influenza vaccination uptake among Kaiser Permanente Northern California (KPNC) and Kaiser Permanente Mid Atlantic States (KPMAS) eligible members during the 2024-2025 influenza season.

Condition or disease

Cardiovascular Diseases

Influenza

Behavior, Social

Intervention/treatment

Cardiovascular-Focused Nudge Communication

Phase

NA

Detailed Description:

In randomized clinical trials and observational studies, influenza vaccination is effective in reducing influenza-related illness and hospitalizations and potentially cardiovascular events and mortality in select populations. However, the potential population level benefit of influenza vaccination is limited by its uptake. Novel implementation strategies to improve vaccination uptake are needed. KP VACCINATE is a multicenter, sequential, individual-level randomized controlled implementation trial examining the effectiveness of a CV-focused nudging communication vs. usual care communication on influenza vaccination uptake among Kaiser Permanente Northern California (KPNC) and Kaiser Permanente Mid Atlantic States (KPMAS) eligible members during the 2024-2025 influenza season. The study will evaluate an operational directive at KPNC and KPMAS. Eligible participants will be randomized into 4 study arms, corresponding to the messaging received at two different vaccine communication touchpoints (Touchpoint 1/Touchpoint 2) during the 2024-2025 influenza season: 1. CV-focused nudge communication/CV-focused nudge communication 2. CV-focused nudge communication/Usual care communication 3. Usual care communication/CV-focused nudge communication 4. Usual care communication/Usual care communication

Study Type : INTERVENTIONAL
Estimated Enrollment : 3750000 participants
Masking : TRIPLE
Primary Purpose : OTHER
Official Title : Kaiser Permanente VACCination Improvement with Nudge-based CardiovAscular Targeted Engagement
Actual Study Start Date : 2024-09-05
Estimated Primary Completion Date : 2025-08-31
Estimated Study Completion Date : 2026-03-31

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: 1
Criteria
Inclusion Criteria
  • 1. Age ≥18 years
  • 2. Active KPNC or KPMAS member
  • 3. ≥6 months of continuous health plan coverage and prescription drug benefit before September 1, 2024
  • 4. Evidence of member access to the KP HealthConnect® Portal and/or a listed registered email address
  • 5. No documented influenza vaccination during the 2024-2025 influenza season prior to randomization
Exclusion Criteria
  • 1. Unable to receive or opted out of receiving health system messaging
  • 2. Other exclusion that prevents messaging outreach.
  • 3. Unknown service area or medical center affiliation.
Kaiser Permanente VACCination Improvement with Nudge-based CardiovAscular Targeted Engagement

Location Details

NCT06571747

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How to Participate

Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.

Locations

RECRUITING

United States, California

Kaiser Permanente Northern California

Pleasanton, California, United States, 94588

RECRUITING

United States, Maryland

Kaiser Permanente Mid Atlantic States

Bethesda, Maryland, United States, 20852