Apnimade
The combination drug composed of aroxybutynin and atomoxetine, designated AD109, is being developed by Apnimed for the treatment of obstructive sleep apnea (OSA). The present study is a Phase 3 open label continuation protocol enrolling qualifying participants who completed one of the parent Phase 3 double-blind placebo-controlled studies, APC-APN-304 or APC-APN-305.
OSA
Aroxybutynin and Atomoxetine
PHASE3
| Study Type : | INTERVENTIONAL |
| Estimated Enrollment : | 1280 participants |
| Masking : | NONE |
| Primary Purpose : | OTHER |
| Official Title : | A Phase 3 Open Label Continuation Protocol of a Fixed Dose Combination of Aroxybutynin and Atomoxetine (AD109) in Obstructive Sleep Apnea |
| Actual Study Start Date : | 2024-07-03 |
| Estimated Primary Completion Date : | 2026-06-30 |
| Estimated Study Completion Date : | 2026-06-30 |
Information not available for Arms and Intervention/treatment
| Ages Eligible for Study: | 18 Years |
| Sexes Eligible for Study: | ALL |
| Accepts Healthy Volunteers: | 1 |
Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.
Not yet recruiting
Sleep Disorders Center of America
Birmingham, alabama, United States, 35213
Not yet recruiting
The University of Alabama/Institute for Rural Health Research
Tuscaloosa, alabama, United States, 35401
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Desert Clinical Reserach, LLC/CCT Research
Mesa, arizona, United States, 85213
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Foothills Research Center/CCT Research
Phoenix, arizona, United States, 85044
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Fiel Family and Sports Medicine/CCT Research
Tempe, arizona, United States, 85283
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Preferred Research Partners, Inc.
Little Rock, arkansas, United States, 72211
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Orange County Research Institute
Anaheim, California, United States, 92801
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Core Healthcare Group
Cerritos, California, United States, 90703
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Exalt Clinical Research, Inc.
Chula Vista, California, United States, 91910
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Collaborative Neuroscience Research, LLC
Los Alamitos, California, United States, 90720
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Empire Clinical Research
Pomona, California, United States, 91767
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Probe Clinical Research Corporation
Riverside, California, United States, 92501
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Pacific Research Network
San Diego, California, United States, 92103
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TriValley Sleep Center
San Ramon, California, United States, 94583
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Providere Research Inc.
West Covina, California, United States, 91790
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Teradan Clinical Trials
Brandon, florida, United States, 33511
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Nouvelle Clinical Research
Cutler Bay, florida, United States, 33189
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Arrow Clinical Trials
Daytona Beach, florida, United States, 32117
Not yet recruiting
Canvas Clinical Research
Lake Worth, florida, United States, 33467
Not yet recruiting
Florida Lung & Sleep Associates
Lehigh Acres, florida, United States, 33971
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Advanced Medical Research Institute
Miami, florida, United States, 33174
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PharmaDev Clinical Research Institute, LLC
Miami, florida, United States, 33176
Not yet recruiting
Flourish Research
Miami, florida, United States, 33186
Not yet recruiting
Renstar Medical Research
Ocala, florida, United States, 34470
Not yet recruiting
Clinical Neuroscience Solutions, Inc.
Orlando, florida, United States, 32801
Not yet recruiting
Central Florida Pediatric Sleep Disorders d/b/a Florida Pediatric Institute, LLC
Winter Park, florida, United States, 32789
Not yet recruiting
Clinical Site Partners, LLC dba Flourish Research
Winter Park, florida, United States, 32789
Not yet recruiting
Neurotrials Research Inc
Atlanta, Georgia, United States, 30328
Not yet recruiting
Atlanta Center for Medical Research
Atlanta, Georgia, United States, 30331
Not yet recruiting
Georgia Neurology and Sleep Medicine Associates
Suwanee, Georgia, United States, 30024
Not yet recruiting
Medster Research
Valdosta, Georgia, United States, 31605
Not yet recruiting
Chicago Research Center, Inc.
Chicago, Illinois, United States, 60634
Not yet recruiting
Advanced ENT and Allergy
Louisville, Kentucky, United States, 40220
Not yet recruiting
Centennial Medical Group Research Department
Columbia, Maryland, United States, 21045
Not yet recruiting
Sleep Disorders Centers of the Mid-Atlantic
Glen Burnie, Maryland, United States, 21061
Not yet recruiting
Velocity Clinical Research
Rockville, Maryland, United States, 20854
Not yet recruiting
Infinity Medical Research
North Dartmouth, Massachusetts, United States, 02747
Not yet recruiting
Revive Research Institute, Inc.
Lathrup Village, road cancer, United States, 48076
Not yet recruiting
Clinical Neurophysiology Services PC
Sterling Heights, road cancer, United States, 48314
Not yet recruiting
Sleep Medicine and Research Center, St. Luke's Hospital
Chesterfield, Missouri, United States, 63017
Not yet recruiting
Healthcare Research Network
Hazelwood, Missouri, United States, 63042
Not yet recruiting
Clayton Sleep Institute, LLC
St. Louis, Missouri, United States, 63123
Not yet recruiting
Henderson Clinical Trials
Henderson, Nevada, United States, 89052
Not yet recruiting
Las Vegas Clinical Trials, LLC
North Las Vegas, Nevada, United States, 89030
Not yet recruiting
Clinilabs Drug Development Corporation
Eatontown, New Jersey, United States, 07724
Not yet recruiting
Sleep Dynamics
Neptune, New Jersey, United States, 07753
Not yet recruiting
Maimonides Sleep Arts & Sciences
Albuquerque, New Mexico, United States, 87107
Not yet recruiting
Research Carolina Elite
Denver, North Carolina, United States, 28037
Not yet recruiting
Advanced Respiratory and Sleep Medicine
Huntersville, North Carolina, United States, 28078
Not yet recruiting
Accellacare
Wilmington, North Carolina, United States, 28412
Not yet recruiting
Small Chair Research
Fargo, North Dakota, United States, 58104
Not yet recruiting
CTI Clinical Research Center
Cincinnati, Ohio, United States, 45212
Not yet recruiting
Intrepid Research, LLC
Cincinnati, Ohio, United States, 45245
Not yet recruiting
Abington Neurological Associates
Abington, Pennsylvania, United States, 19001
Not yet recruiting
Respiratory Specialists
Wyomissing, Pennsylvania, United States, 19610
Not yet recruiting
Tribe Clinical Research, LLC
Greenville, South Carolina, United States, 29607
Not yet recruiting
Velocity Clinical Research, Greenville
Greenville, South Carolina, United States, 29615
Not yet recruiting
OnSite Clinical Solutions, LLC
Rock Hill, South Carolina, United States, 29732
Not yet recruiting
FutureSearch Trials of Neurology
Austin, Texas, United States, 78731
Not yet recruiting
FutureSearch Trials of Dallas
dallas, Texas, United States, 75231
Not yet recruiting
Memorial Hermann Village
Houston, Texas, United States, 77043
Not yet recruiting
Houston Clinical Research Associates
Houston, Texas, United States, 77070
Not yet recruiting
Huntsville Research Institute
Huntsville, Texas, United States, 77340
Not yet recruiting
Element Research Group
Saint Anthony, Texas, United States, 78258
Not yet recruiting
South Ogden Family Medicine/CCT Research
South Ogden, Utah, United States, 84405
Not yet recruiting
Medical Arts Health Research Group
Kelowna, British Columbia, Canada, VIY 4N7
Not yet recruiting
AMNDX Inc
Markham, Ontario, Canada, L3R 1A3
Not yet recruiting
Canadian Phase Onward Inc.
Toronto, Ontario, Canada, oe3h 0k2
Not yet recruiting
Warrior Tition, Ins.
Toronto, Ontario, Canada, Shame on