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NCT06536543 | RECRUITING | Acute Respiratory Distress Syndrome

EIT Assessment of Overdistension in ARDS Patients in Prone Position
Sponsor:

University Hospital, Bordeaux

Brief Summary:

Mechanical ventilation in ARDS requires protective ventilation with low VT and PEEP. PEEP titration can improve lung recruitment in the dependent lung but with a risk of overdistension in the non-dependant lung. EIT can measure the distribution of tidal ventilation and assess overdistension and collapse during a PEEP titration in any position (prone or not). This study aims to measure the best PEEP as a compromise between recruitment and overdistension during a PEEP trial with EIT before and just after PP.

Condition or disease

Acute Respiratory Distress Syndrome

Intervention/treatment

Acute Respiratory Distress Syndrom (ARDS) treated with Prone Position (PP) equipped with Electrical Impedance Tomography (EIT)

Study Type : OBSERVATIONAL
Estimated Enrollment : 20 participants
Official Title : Pulmonary Overdistension Assessment with Electrical Impedance Tomography in Patients with Acute Respiratory Distress Syndrom in Prone Position
Actual Study Start Date : 2024-10-15
Estimated Primary Completion Date : 2025-10
Estimated Study Completion Date : 2025-10

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • * Patients hospitalized in the ICU and who suffered moderate or severe ARDS (Berlin criteria, PaO2/FiO2\<150), intubated sedated, under myorelaxant and equipped with EIT
  • * Over the age of 18.
Exclusion Criteria
  • * Broncho-pleural leaks
  • * Pregnant or breastfeeding woman.
  • * Guardianship or curatorship
  • * Deprived of liberty
  • * No health insurance
  • * Impossibility to correctly position the EIT belt (e.g., dressings, chest drainage, etc.)
  • * Contra indications to EIT (e.g., implantable cardiac defibrillator, pacemaker, instable spinal lesions)
EIT Assessment of Overdistension in ARDS Patients in Prone Position

Location Details

NCT06536543

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How to Participate

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Locations

RECRUITING

France,

Haut-Lévêque Hospital

Pessac, France, 33604